Limb Salvage Resection of Massive Dedifferentiated Thigh Liposarcoma in a Patient Lost to Follow-Up.
Autor: | Calvo NJ; Surgery, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA., Mann AJ; Surgery, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA., Lopez-Viego M; Surgery, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.; Surgery, Bethesda Hospital East, Baptist Health South Florida, Boynton Beach, USA., Genuit T; Surgery, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA. |
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Jazyk: | angličtina |
Zdroj: | Cureus [Cureus] 2021 Feb 15; Vol. 13 (2), pp. e13356. Date of Electronic Publication: 2021 Feb 15. |
DOI: | 10.7759/cureus.13356 |
Abstrakt: | Dedifferentiated liposarcoma (DDL) is a rare soft tissue tumor that represents a non-lipogenic progression of well-differentiated liposarcoma (WDL). Unlike WDL, DDL has the propensity for metastasis and is associated with an increased incidence of local recurrence. For DDL of the extremities that is resectable with acceptable functional outcomes, treatment includes primary surgical resection with negative margins. Although rare due to advances in reconstructive techniques, amputation for DDL of the extremities should be considered in which appropriate tumor resection cannot be performed without adequate preservation of limb function. We present the clinical progression of a patient with a large DDL of the right thigh who was initially lost to follow-up, but ultimately underwent delayed definitive therapy with the intent for limb salvage. This case illustrates the importance of assessing neurovascular, osseous, and soft tissue involvement to properly predict and preserve limb function while achieving adequate tumor resection. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Calvo et al.) |
Databáze: | MEDLINE |
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