SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)-pilot: A feasibility study.
| Autor: | Chew KA; Memory, Ageing and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore., Xu X; Memory, Ageing and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.; School of Public Health and the 2nd Affiliated Hospital of School of Medicine Zhejiang University Hangzhou China., Siongco P; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore., Villaraza S; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore., Phua AKS; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore., Wong ZX; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore., Chung CY; Clinical Nutrition Research Centre Singapore Institute for Clinical Sciences Agency for Science, Technology and Research (ASTAR) Singapore Singapore., Tang N; Division of Neurology, Department of Medicine National University Hospital Singapore Singapore., Chew E; Division of Neurology, Department of Medicine National University Hospital Singapore Singapore.; Department of Medicine, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore., Henry CJ; Clinical Nutrition Research Centre Singapore Institute for Clinical Sciences Agency for Science, Technology and Research (ASTAR) Singapore Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.; Singapore Institute of Food and Biotechnology Innovation, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore., Koo E; Departments of Medicine and Physiology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore., Chen C; Memory, Ageing and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore. |
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| Jazyk: | angličtina |
| Zdroj: | Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2021 Mar 15; Vol. 7 (1), pp. e12141. Date of Electronic Publication: 2021 Mar 15 (Print Publication: 2021). |
| DOI: | 10.1002/trc2.12141 |
| Abstrakt: | Introduction: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi-domain lifestyle interventions compared to Singaporean adaptations. Methods: Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months. Results: Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups ( P Discussion: This study is the first to compare the feasibility of multi-domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi-domain lifestyle interventions in preventing cognitive decline. Competing Interests: None declared. (© 2020 The Authors. Alzheimer's & Dementia: Translational Research & Clinical Interventions published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association.) |
| Databáze: | MEDLINE |
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