Can the insecticide Imidacloprid affect the health of the Neotropical freshwater fish Astyanax altiparanae (Teleostei: Characidae)?

Autor: Almeida ÉC; Natural Resources Institute, Federal University of Itajubá, Av. BPS, Pinheirinho, Itajubá, MG, CEP 37500-903, Brazil; Department of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, Bl. 17, São Paulo, SP, CEP 05508-900, Brazil. Electronic address: erykaca@usp.br., Passos LS; Department of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, Bl. 17, São Paulo, SP, CEP 05508-900, Brazil. Electronic address: larissapassos@usp.br., Vieira CED; Laboratory of Animal Ecophysiology, Department of Physiological Sciences, State University of Londrina, Rod. Celso Garcia Cid, Londrina, PR, CEP 86057-970, Brazil. Electronic address: carlosuenp@gmail.com., Acayaba RD; Environmental Chemistry Laboratory, Institute of Chemistry, State University of Campinas. Cidade Universitária Zeferino Vaz, Barão Geraldo, Campinas, SP, CEP 13083-970, Brazil. Electronic address: raphael.acayaba@hotmail.com., Montagner CC; Environmental Chemistry Laboratory, Institute of Chemistry, State University of Campinas. Cidade Universitária Zeferino Vaz, Barão Geraldo, Campinas, SP, CEP 13083-970, Brazil. Electronic address: ccmonta@unicamp.br., Pinto E; Department of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, Bl. 17, São Paulo, SP, CEP 05508-900, Brazil. Electronic address: ernani@usp.br., Martinez CBDR; Laboratory of Animal Ecophysiology, Department of Physiological Sciences, State University of Londrina, Rod. Celso Garcia Cid, Londrina, PR, CEP 86057-970, Brazil. Electronic address: cbueno@uel.br., Fonseca AL; Natural Resources Institute, Federal University of Itajubá, Av. BPS, Pinheirinho, Itajubá, MG, CEP 37500-903, Brazil. Electronic address: afonseca@unifei.edu.br.
Jazyk: angličtina
Zdroj: Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2021 Jul; Vol. 85, pp. 103634. Date of Electronic Publication: 2021 Mar 16.
DOI: 10.1016/j.etap.2021.103634
Abstrakt: Female juveniles of the Neotropical fish Astyanax altiparanae were exposed for 96 h to four treatments containing the active ingredient from Imidacloprid® commercial formulation (IMI 1, IMI 2, IMI 3, and IMI 4) and to a control treatment (only dechlorinated tap water). Glutathione content, glutathione S-transferase activity, lipid peroxidation (LPO) and protein carbonylation levels, acetylcholinesterase (AChE) activity, and frequency of micronuclei and erythrocyte nuclear abnormalities (ENA) were measured in the fish. The muscle and gills were the most affected organs; their antioxidant defense was not enough to prevent oxidative damage (LPO) in the IMI 2 and IMI 4 treatment fish. IMI also inhibited AChE activity in the muscle (IMI 3 and IMI 4) and increased ENA frequency (IMI 4). IMI can affect the health of A. altiparanae in environmentally relevant concentrations, causing oxidative damage in different organs, neurotoxic effects in the muscle, and genotoxicity.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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