Impact of chronic endometritis in infertility: a SWOT analysis.

Autor: Espinós JJ; Fertty, Barcelona, Spain, Universidad Autónoma de Barcelona, Bellaterra Barcelona, Spain. Electronic address: JEspinos@santpau.cat., Fabregues F; Institut Clinic Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic Barcelona, Spain., Fontes J; Hospital Universitario Virgen de las Nieves, Granada, Spain., García-Velasco JA; IVI RMA Madrid, Madrid, Spain., Llácer J; Instituto Bernabeu Alicante, Alicante, Spain., Requena A; IVI RMA Madrid, Madrid, Spain., Checa MÁ; Hospital del Mar-Parc de Salut Mar Barcelona, Spain., Bellver J; Departamento de Pediatría, Obstetricia y Ginecología, Facultad de Medicina, Universidad de Valencia, Spain, Instituto Valenciano de Infertilidad (IVI-RMA) Valencia, Valencia, Spain.
Jazyk: angličtina
Zdroj: Reproductive biomedicine online [Reprod Biomed Online] 2021 May; Vol. 42 (5), pp. 939-951. Date of Electronic Publication: 2021 Feb 11.
DOI: 10.1016/j.rbmo.2021.02.003
Abstrakt: Chronic endometritis is a pathology often associated with reproductive failure, but there are still no clear recommendations on whether its inclusion in the initial study of infertile couples is necessary. In this discussion paper, based on a SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis, the different aspects of the repercussions of chronic endometritis in fertility are evaluated. To avoid possible subjectivity in the analysis and results of this study, the researchers followed the Oxford criteria for the evaluation of evidence. The results from the evaluation of the reviewed literature seem to indicate that, pending new evidence, it would be advisable not to include chronic endometritis in the initial baseline study before assisted reproduction in order not to delay other assisted reproduction treatments. However, it would be advisable in cases of repetitive implantation failure and pregnancy loss after having undergone IVF with viable embryos and before continuing with costly reproductive processes, since results could be improved. The development of randomized studies assessing the impact of antibiotic treatment as a possible therapeutic option in infertile women with chronic endometritis, as well as the possible impact on endometrial microbiota and receptivity/implantation, would allow for the establishment of more precise clinical guidelines in this regard.
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Databáze: MEDLINE
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