Non-invasive fractional flow reserve (FFR CT ) in the evaluation of acute chest pain - Concepts and first experiences.

Autor: Fischer AM; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Facility Mannheim, Heidelberg University, Heidelberg, Germany., van Assen M; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; University Medical Center Groningen, Center for Medical Imaging, Department of Radiology, Groningen, the Netherlands., Schoepf UJ; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC, United States. Electronic address: schoepf@musc.edu., Matuskowitz AJ; Division of Emergency Medicine, Department of Emergency Medicine, Medical University of South Carolina, Charleston, SC, United States., Varga-Szemes A; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States., Golden JW; Division of Internal Medicine, Department of Medicine, Medical University of South Carolina, Charleston, SC, United States., Giovagnoli DA; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States., Tesche C; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Department of Cardiology and Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich, Germany; Department of Cardiology, Munich University Clinic, Ludwig-Maximilians-University, Munich, Germany., Bayer RR 2nd; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC, United States.
Jazyk: angličtina
Zdroj: European journal of radiology [Eur J Radiol] 2021 May; Vol. 138, pp. 109633. Date of Electronic Publication: 2021 Mar 08.
DOI: 10.1016/j.ejrad.2021.109633
Abstrakt: Objective: To evaluate 30 day rate of major adverse cardiac events (MACE) utilizing cCTA and FFR CT for evaluation of patients presenting to the Emergency Department (ED) with acute chest pain.
Materials and Methods: Patients between the ages of 18-95 years who underwent clinically indicated cCTA and FFR CT in the evaluation of acute chest pain in the emergency department were retrospectively evaluated for 30 day MACE, repeat presentation/admission for chest pain, revascularization, and additional testing.
Results: A total of 59 patients underwent CCTA and subsequent FFR CT for the evaluation of acute chest pain in the ED over the enrollment period. 32 out of 59 patients (54 %) had negative FFR CT (>0.80) out of whom 18 patients (55 %) were discharged from the ED. Out of the 32 patients without functionally significant CAD by FFR CT , 32 patients (100 %) underwent no revascularization and 32 patients (100 %) had no MACE at the 30-day follow-up period.
Conclusion: In this limited retrospective study, patients presenting to the ED with acute chest pain and with CCTA with subsequent FFR CT of >0.8 had no MACE at 30 days; however, for many of these patients results were not available at time of clinical decision making by the ED physician.
(Copyright © 2021. Published by Elsevier B.V.)
Databáze: MEDLINE
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