| Autor: |
Omarov YA; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Veselova TN; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Shakhnovich RM; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Sukhinina TS; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Zhukova NS; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Merkulova IN; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Pevzner DV; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Arutunyan GK; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Mironov VM; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Merkulov EV; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Samko AN; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow., Ternovoy SK; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow; I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow., Staroverov II; National medical research center of cardiology» of the Ministry of healthcare of the Russian Federation, Moscow. |
| Abstrakt: |
Aim To evaluate the diagnostic accuracy of cardiac perfusion computed tomography (PCT) with transesophageal electrocardiostimulation (TE ECS) for detection of ischemia in patients with borderline coronary stenosis (50-75 %) compared to measurements of fractional flow reserve (FFR).Material and methods The study included 25 patients with borderline (50-75 %) coronary stenosis as per data of computed tomography angiography (CTA) or coronary angiography (CAG). Later the patients underwent invasive measurement of FFR and cardiac PCT on a 320-row detector tomograph in combination with the TE ECS stress test. FFR values <0.8 indicated the hemodynamic significance of stenosis. Myocardial perfusion was evaluated visually based on consensus of two experts.Results All patients completed the study protocol. Cardiac pacing duration was 6 min for all patients. Four patients required intravenous administration of atropine sulphate. PCT with TE ECS detected significant for FFR stenoses with sensitivity, specificity, and predictive value of a positive result and predictive value for a negative result of 47, 90, 87, and 53 %, respectively.Conclusion PCT with TE ECS in combination with CTA can be considered as an informative method for simultaneous evaluation of the condition of coronary arteries and detection of myocardial ischemia. This method is particularly relevant for assessing the hemodynamic significance of borderline coronary stenoses. |
