| Autor: |
Iñiguez-Luna MI; Postgrado de Innovación en Manejo de Recursos Naturales Colegio de Posgraduados, Campus San Luis Potosí, Salinas de Hidalgo, Iturbide 73, 78620, San Luis Potosí, Mexico.; Grupo Interdisciplinario de Investigación en Sechium edule en México, A.C. Agustín Melgar 10 Col. Niños Héroes, 56108, Texcoco, Estado de México, Mexico., Cadena-Iñiguez J; Postgrado de Innovación en Manejo de Recursos Naturales Colegio de Posgraduados, Campus San Luis Potosí, Salinas de Hidalgo, Iturbide 73, 78620, San Luis Potosí, Mexico. jocadena@gmail.com.; Grupo Interdisciplinario de Investigación en Sechium edule en México, A.C. Agustín Melgar 10 Col. Niños Héroes, 56108, Texcoco, Estado de México, Mexico. jocadena@gmail.com., Soto-Hernández RM; Programa de Botánica Colegio de Postgraduados, Km. 36.5 Carretera México-Texcoco, 56230, Texcoco, Estado de México, Mexico. msoto@colpos.mx.; Grupo Interdisciplinario de Investigación en Sechium edule en México, A.C. Agustín Melgar 10 Col. Niños Héroes, 56108, Texcoco, Estado de México, Mexico. msoto@colpos.mx., Morales-Flores FJ; Postgrado de Innovación en Manejo de Recursos Naturales Colegio de Posgraduados, Campus San Luis Potosí, Salinas de Hidalgo, Iturbide 73, 78620, San Luis Potosí, Mexico.; Grupo Interdisciplinario de Investigación en Sechium edule en México, A.C. Agustín Melgar 10 Col. Niños Héroes, 56108, Texcoco, Estado de México, Mexico., Cortes-Cruz M; Centro Nacional de Recursos Genéticos-INIFAP, Boulevard de la Biodiversidad 300, 47600, Tepatitlán de Morelos, Jalisco, Mexico.; Grupo Interdisciplinario de Investigación en Sechium edule en México, A.C. Agustín Melgar 10 Col. Niños Héroes, 56108, Texcoco, Estado de México, Mexico., Watanabe KN; Tsukuba Plant Innovation Research Center, University of Tsukuba, Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki Prefecture, 305-8571, Japan., Machida-Hirano R; Genetic Resources Center, National Agriculture and Food Research Organization, 2-1-2 Kannondai, Tsukuba, Ibaraki, 305-8602, Japan., Cadena-Zamudio JD; Grupo Interdisciplinario de Investigación en Sechium edule en México, A.C. Agustín Melgar 10 Col. Niños Héroes, 56108, Texcoco, Estado de México, Mexico.; Instituto de Ecología, A. C., Carretera Antigua a Coatepec 351, El Haya, 91070, Xalapa, Veracruz, Mexico. |
| Abstrakt: |
Bioprospecting identifies new sources of compounds with actual or potential economic value that come from biodiversity. An analysis was performed regarding bioprospecting purposes in ten genotypes of Sechium spp., through a meta-analysis of 20 information sources considering different variables: five morphological, 19 biochemical, anti-proliferative activity of extracts on five malignant cell lines, and 188 polymorphic bands of amplified fragment length polymorphisms, were used in order to identify the most relevant variables for the design of genetic interbreeding. Significant relationships between morphological and biochemical characters and anti-proliferative activity in cell lines were obtained, with five principal components for principal component analysis (SAS/ETS); variables were identified with a statistical significance (< 0.7 and Pearson values ≥ 0.7), with 80.81% of the accumulation of genetic variation and 110 genetic bands. Thirty-nine (39) variables were recovered using NTSYSpc software where 30 showed a Pearson correlation (> 0.5) and nine variables (< 0.05), Finally, using a cladistics analysis approach highlighted 65 genetic bands, in addition to color of the fruit, presence of thorns, bitter flavor, piriform and oblong shape, and also content of chlorophylls a and b, presence of cucurbitacins, and the IC 50 effect of chayote extracts on the four cell lines. |
