Gabapentinoids for Pruritus in Older Adults: A Narrative Review.
| Autor: | Sreekantaswamy SA; San Francisco Department of Dermatology, University of California, San Francisco, CA, USA.; School of Medicine, University of Utah, Salt Lake City, UT, USA., Mollanazar N; Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA., Butler DC; San Francisco Department of Dermatology, University of California, San Francisco, CA, USA. Daniel.Butler@UCSF.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Dermatology and therapy [Dermatol Ther (Heidelb)] 2021 Jun; Vol. 11 (3), pp. 669-679. Date of Electronic Publication: 2021 Mar 15. |
| DOI: | 10.1007/s13555-021-00513-z |
| Abstrakt: | There is currently no standardized algorithm for the treatment of chronic pruritus (CP), or itch lasting more than 6 weeks, in adults aged ≥ 65 years. The antiepileptic agents gabapentin and pregabalin, however, are gaining popularity in the dermatologic community for their efficacy in treating CP of neuropathic origin. Yet the lack of literature specifically looking at the safety and efficacy of these medications in older adults results in limited guidance for providers in the safe use of gabapentinoids. In this paper we discuss special considerations and recommendations for treating older adults with gabapentin and pregabalin and explore the possibility for these drugs to ameliorate CP of multiple etiologies. |
| Databáze: | MEDLINE |
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