Metabolism in Invariant Natural Killer T Cells: An Overview.

Autor: Yarosz EL; Immunology Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Chang CH; Immunology Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Kumar A; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Jazyk: angličtina
Zdroj: Immunometabolism [Immunometabolism] 2021; Vol. 3 (2). Date of Electronic Publication: 2021 Feb 10.
DOI: 10.20900/immunometab20210010
Abstrakt: Cellular metabolism is critical for generating energy and macromolecules for cell growth and survival. In recent years, the importance of metabolism in mediating T cell differentiation, proliferation, and function has been a hot topic of investigation. However, very little is known about metabolic regulation in invariant natural killer T (iNKT) cells. In this viewpoint, we will discuss what is currently known about immunometabolism in iNKT cells and how these findings relate to CD4 T cells.
Competing Interests: CONFLICTS OF INTEREST The authors declare no conflicts of interest.
Databáze: MEDLINE