Metabolism in Invariant Natural Killer T Cells: An Overview.
Autor: | Yarosz EL; Immunology Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Chang CH; Immunology Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Kumar A; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. |
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Jazyk: | angličtina |
Zdroj: | Immunometabolism [Immunometabolism] 2021; Vol. 3 (2). Date of Electronic Publication: 2021 Feb 10. |
DOI: | 10.20900/immunometab20210010 |
Abstrakt: | Cellular metabolism is critical for generating energy and macromolecules for cell growth and survival. In recent years, the importance of metabolism in mediating T cell differentiation, proliferation, and function has been a hot topic of investigation. However, very little is known about metabolic regulation in invariant natural killer T (iNKT) cells. In this viewpoint, we will discuss what is currently known about immunometabolism in iNKT cells and how these findings relate to CD4 T cells. Competing Interests: CONFLICTS OF INTEREST The authors declare no conflicts of interest. |
Databáze: | MEDLINE |
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