Fear Memory Relapse: The Importance of Input Associativity.

Autor: Mermet-Joret N; DANDRITE, The Danish Research Institute of Translational Neuroscience, Aarhus University, Aarhus, Denmark; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark; Center for Proteins in Memory - PROMEMO, Danish National Research Foundation, Aarhus University, Aarhus, Denmark. Electronic address: nmj@dandrite.au.dk., Capogna M; DANDRITE, The Danish Research Institute of Translational Neuroscience, Aarhus University, Aarhus, Denmark; Center for Proteins in Memory - PROMEMO, Danish National Research Foundation, Aarhus University, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Nabavi S; DANDRITE, The Danish Research Institute of Translational Neuroscience, Aarhus University, Aarhus, Denmark; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark; Center for Proteins in Memory - PROMEMO, Danish National Research Foundation, Aarhus University, Aarhus, Denmark.
Jazyk: angličtina
Zdroj: Trends in neurosciences [Trends Neurosci] 2021 May; Vol. 44 (5), pp. 337-339. Date of Electronic Publication: 2021 Mar 09.
DOI: 10.1016/j.tins.2021.02.006
Abstrakt: An inherent property of extinguished fear memories is that the fear may return. A recent study in mice by Li et al. provides novel insights into the mechanisms underlying the relapse of an extinguished memory through converging sensory and contextual cues from the auditory cortex (ACx) and ventral hippocampus (vHPC) to the lateral amygdala (LA).
Competing Interests: Declaration of Interests The authors declare no competing interests in relation to this work.
(Copyright © 2021 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE