Epidemiological and clinical profile between influenza A and B virus in Costa Rican children.

Autor:	Ávila-Morales S; Servicio de Infectología, Hospital Nacional de Niños 'Dr. Carlos Sáenz Herrera', Centro de Ciencias Médicas, Caja Costarricense de Seguro Social (CCSS), San José, Costa Rica., Ospina-Henao S; Instituto de Investigación en Ciencias Médicas (IICIMED), Escuela de Medicina, Universidad de Ciencias Médicas (UCIMED) San José, Costa Rica., Ulloa-Gutierrez R; Servicio de Infectología, Hospital Nacional de Niños 'Dr. Carlos Sáenz Herrera', Centro de Ciencias Médicas, Caja Costarricense de Seguro Social (CCSS), San José, Costa Rica; Instituto de Investigación en Ciencias Médicas (IICIMED), Escuela de Medicina, Universidad de Ciencias Médicas (UCIMED) San José, Costa Rica., Ávila-Agüero ML; Servicio de Infectología, Hospital Nacional de Niños 'Dr. Carlos Sáenz Herrera', Centro de Ciencias Médicas, Caja Costarricense de Seguro Social (CCSS), San José, Costa Rica; Instituto de Investigación en Ciencias Médicas (IICIMED), Escuela de Medicina, Universidad de Ciencias Médicas (UCIMED) San José, Costa Rica; Affiliated Researcher, Center for Infectious Disease Modeling and Analysis (CIDMA), Yale University, New Haven CT, USA. Electronic address: mlavila@ccss.sa.cr.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Apr; Vol. 105, pp. 763-768. Date of Electronic Publication: 2021 Mar 09.
DOI:	10.1016/j.ijid.2021.03.006
Abstrakt:	Objective: We aimed to evaluate the clinical and epidemiological behavior of influenza type A versus type B and analyze if there was any correlation or differences between the characteristics of both groups. Methods: An observational, retrospective, descriptive, and population-based study based of children who were hospitalized at the only national pediatric hospital of Costa Rica from January 1, 2010 to December 31, 2018 and had a confirmed influenza virus infection. Results: 336 patients were analyzed. Mean age was 35,6 ± 36,7 months (3,0 ± 3,1 years). The only significant variables at 25% in relation to influenza type A or B virus were: sex, month of diagnosis, fever, vomiting, cough, use of antibiotics and admission to the PICU. The hospitalization rate at our hospital increased between the months of October to December, with a higher percentage of cases in November and December, which reveals that the "real peak" in our population begins between 3 to 4 months after the end of the vaccination campaign. Patients with influenza A virus had a 2.5 times greater risk of being admitted to the PICU. Mortality rate was 0.6% and 0% among influenza A and B children, respectively. Conclusions: Variables in which a causality was found with type A or B virus were: admission to the PICU, month of diagnosis, and cough. However, influenza B clinical behavior continues to be unpredictable. (Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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