| Autor: |
Mulders JW; Department of Biochemistry, University of Nijmegen, The Netherlands., Voorter CE, Lamers C, de Haard-Hoekman WA, Montecucco C, van de Ven WJ, Bloemendal H, de Jong WW |
| Jazyk: |
angličtina |
| Zdroj: |
Current eye research [Curr Eye Res] 1988 Feb; Vol. 7 (2), pp. 207-19. |
| DOI: |
10.3109/02713688808995750 |
| Abstrakt: |
A major protein with a molecular weight of 17,000, designated as MP17, has been identified in mammalian eye lens plasma membranes. Hydrophobic photolabeling experiments revealed that MP17 is a genuine intrinsic membrane protein. By using monoclonal antibodies we demonstrated that MP17 is not detectable in liver, heart, muscle, spleen and kidney, and thus can be considered, like MP26, as a lens-specific membrane protein. Furthermore, we showed that MP17 is a substrate for cAMP-dependent protein kinase and that it is a calmodulin-binding protein. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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