Is Carbapenem-resistant Klebsiella pneumoniae Infection in Pediatric Bone Marrow Transplantation Recipients Inevitably Fatal?

Autor: Komitopoulou A; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Paisiou A; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Oikonomopoulou C; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Kaisari K; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Ioannidou ED; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Tzannou I; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Sipsas NV; Infectious Diseases Unit, Department of Pathophysiology, Laikon General Hospital and Medical School, National and Kapodistrian University of Athens, Athens, Greece., Vessalas G; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Peristeri I; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Goussetis E; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'., Kitra V; Stem Cell Transplant Unit, 'Agia Sofia Children's Hospital'.
Jazyk: angličtina
Zdroj: Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2022 Mar 01; Vol. 44 (2), pp. e456-e459.
DOI: 10.1097/MPH.0000000000002142
Abstrakt: Carbapenem resistance, most notably in Klebsiella pneumonia (KPC), results in infections associated with significant morbidity and mortality. Here we report 2 cases of adolescent patients with KPC infection after high-risk bone marrow transplantation, who eventually succumbed from other causes and review the epidemiology and treatment options for KPC infections in this vulnerable population.
Competing Interests: The authors declare no conflict of interest.
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Databáze: MEDLINE