Physical capacity, body composition and immune-inflammatory markers are associated with risk of cardiovascular disease in sedentary people living with HIV.
| Autor: | Zanetti HR; Department of Physical Education, IMEPAC University Center, Araguari, Brazil - hugo.zanetti@hotmail.com.; Department of Medicine, IMEPAC University Center, Araguari, Brazil - hugo.zanetti@hotmail.com.; Postgraduate Program in Physical Education, Federal University of Triângulo Mineiro, Uberaba, Brazil - hugo.zanetti@hotmail.com., Soares VL; Postgraduate Program in Physical Education, Federal University of Triângulo Mineiro, Uberaba, Brazil., Soares WF; Postgraduate Program in Physical Education, Federal University of Triângulo Mineiro, Uberaba, Brazil., Lourenço CL; Postgraduate Program in Physical Education, Federal University of Santa Catarina, Florianópolis, Brazil., Gonçalves A; Department of Physical Education, IMEPAC University Center, Araguari, Brazil.; Department of Medicine, IMEPAC University Center, Araguari, Brazil., Lopes LT; Department of Medicine, Brasil University, Fernandópolis, Brazil., Roever L; Postgraduate Program in Health Science, Federal University of Uberlândia, Uberlândia, Brazil., Silva-Vergara ML; Department of Medicine, Federal University of Triângulo Mineiro, Uberaba, Brazil., Neves FF; Department of Medicine, Federal University of Triângulo Mineiro, Uberaba, Brazil., Mendes EL; Postgraduate Program in Physical Education, Federal University of Triângulo Mineiro, Uberaba, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | Minerva cardiology and angiology [Minerva Cardiol Angiol] 2023 Feb; Vol. 71 (1), pp. 5-11. Date of Electronic Publication: 2021 Mar 11. |
| DOI: | 10.23736/S2724-5683.21.05578-X |
| Abstrakt: | Background: People living with HIV (PLHIV) are experiencing a high level of non-HIV-related disease mainly related to cardiovascular system however the factors associated with this scenario are widely discussed and indefinite so far. The purpose was to investigate the association of physical capacities, body composition, and immune-inflammatory markers with the Framingham risk score (FRS) in PLHIV. Methods: Volunteers were recruited and data on age, the time of HIV infection diagnosis and the time of HAART use were collected. The volunteers performed upper limb strength (ULS), lower limb strength (LLS) and cardiorespiratory fitness (VO2peak) tests, body composition evaluation, and blood collection to immune-inflammatory marker markers and the FRS was calculated. Partial age- and sex-adjusted correlation was used to verify associations between factors and multiple linear regression analysis was performed to identify an independent association of FRS and the variables. Results: 113 PLHIV met the eligible criteria and were observed a negative correlation between CD4 + (r=-0.615), time of HIV infection diagnosis (r=-0.237), time of HAART use (r=-0.239), ULS (r=-0.274), LLS (r=-0.213), and VO Conclusions: Environmental and biological HIV-related factors are inversely associated with FRS while immune-inflammation markers have a positive association. |
| Databáze: | MEDLINE |
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