Building a Longitudinal National Integrated Cardiovascular Database　- Lessons Learnt From SingCLOUD.

Autor:	Yeo KK; Department of Cardiology, National Heart Centre Singapore Singapore.; Duke-NUS Medical School Singapore., Ong HY; Department of Cardiology, Khoo Teck Puat Hospital Singapore., Chua T; Department of Cardiology, National Heart Centre Singapore Singapore.; Duke-NUS Medical School Singapore., Lim ZJ; Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne Victoria Australia., Yap J; Department of Cardiology, National Heart Centre Singapore Singapore., Ho HH; Department of Cardiology, Tan Tock Seng Hospital Singapore., Jaufeerally F; Duke-NUS Medical School Singapore.; Department of Internal Medicine, Singapore General Hospital Singapore., Tong KL; Department of Cardiology, Changi General Hospital Singapore., Kojodjojo P; Division of Cardiology, Department of Medicine, Jurong Health Singapore., Wong HB; Biostatistics and Research Branch, Ministry of Health Singapore., Heng D; Public Health Group, Ministry of Health Singapore., Tan KB; Policy Research and Evaluation Division, Ministry of Health Singapore., Richards AM; Cardiovascular Research Institute [CVRI], National University Heart Centre [NUHCS], National University Health System Singapore., Teoh KL; Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital Singapore., Sin K; Department of Cardiothoracic Surgery, National Heart Centre Singapore Singapore., Tan NC; SingHealth Polyclinics Singapore., Lee SBM; National Healthcare Group Polyclinics Singapore., Lim T; Integrated Health Informatics System, Ministry of Health Holdings Singapore., Ta A; Integrated Health Informatics System, Ministry of Health Holdings Singapore., Liok E; Infocomm Media Development Authority of Singapore Singapore., Lau YH; Singapore Cardiac Data Bank, National Heart Centre Singapore Singapore., Gao F; NHRIS, National Heart Centre Singapore Singapore., Liman C; Holmusk Singapore., Sarkar J; Holmusk Singapore., Sahlén A; Department of Cardiology, National Heart Centre Singapore Singapore.; Karolinska Institute Stockholm Sweden., Koh TH; Department of Cardiology, National Heart Centre Singapore Singapore., Chan MY; Cardiac Department, National University Hospital Singapore.
Jazyk:	angličtina
Zdroj:	Circulation reports [Circ Rep] 2019 Dec 07; Vol. 2 (1), pp. 33-43. Date of Electronic Publication: 2019 Dec 07.
DOI:	10.1253/circrep.CR-19-0106
Abstrakt:	Background: Real world data on clinical outcomes and quality of care for patients with coronary artery disease (CAD) are fragmented. We describe the rationale and design of the Singapore Cardiovascular Longitudinal Outcomes Database (SingCLOUD). Methods and Results: We designed a health data grid to integrate clinical, administrative, laboratory, procedural, prescription and financial data from all public-funded hospitals and primary care clinics, which provide 80% of health care in Singapore. Here, we explain our approach to harmonize real-world data from diverse electronic medical and non-medical platforms to develop a robust and longitudinal dataset. We present pilot data on patients with myocardial infarction (MI) treated with percutaneous coronary intervention (PCI) between 2012 and 2014. The initial data set had 53,395 patients. Of these, 35,203 had CAD confirmed on coronary angiography, of whom 21,521 had PCI. Eventually, limiting to 2012-2014, 3,819 patients had MI with PCI, while 5,989 had MI. Compared with the quality improvement registry, Singapore Cardiac Data Bank, which had 189 fields for analysis, the SingCLOUD platform generated an additional 313 additional data fields, and was able to identify an additional 250 heart failure events, 664 major adverse cardiovascular events at 2 years, and low-density lipoprotein levels to 1 year for 3,747 patients. Conclusions: By integrating multiple incongruent data sources, SINGCLOUD enables in-depth analysis of real-world cardiovascular "big data". Competing Interests: C.L. and J.S. are employees of Holmusk. The other authors declare no conflicts of interest. (Copyright © 2020, THE JAPANESE CIRCULATION SOCIETY.)
Databáze:	MEDLINE
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