SARS-CoV-2 Infection in the Heart Transplant Recipient.

Autor: Shah JZ; Department of Cardiology and Cardiovascular Surgery, Heart Hospital, Hamad Medical Corporation, Doha, Qatar., Elbdri S; Department of Cardiology and Cardiovascular Surgery, Heart Hospital, Hamad Medical Corporation, Doha, Qatar., Patel AA; Department of Cardiology and Cardiovascular Surgery, Heart Hospital, Hamad Medical Corporation, Doha, Qatar., Badr AMH; Department of Cardiology and Cardiovascular Surgery, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Jazyk: angličtina
Zdroj: Heart views : the official journal of the Gulf Heart Association [Heart Views] 2020 Jul-Sep; Vol. 21 (3), pp. 220-224. Date of Electronic Publication: 2020 Oct 13.
DOI: 10.4103/HEARTVIEWS.HEARTVIEWS_155_20
Abstrakt: Review of the literature and reported case series has not reported an increased risk of SARS-CoV-2 infection in heart transplant recipients. However, this population is at increased risk of a more severe infection with increased mortality because of age and the presence of multiple comorbid conditions There is no significant difference in presenting symptoms in transplant recipients as compared to nontransplant patients, although diarrhea has been reported to be more frequent in transplant patients, a common side effect of immunosuppressive medications. Standard preventive measures have been shown to be equally protective in heart transplant recipients. Risk factors for severe disease and mortality are similar in both transplant recipients and nontransplant patients and include older age and the presence of comorbidities hypertension being the most common. The SARS-CoV-2 infection did not increase the risk of transplant allograft rejection. Currently, there are no specific treatment recommendations for SARS-CoV-2 infection in transplant recipients. However, the International Society of Heart and Lung and Transplant has issued guidance on how to modulate immunosuppressive therapy during SARS-CoV-2 infection.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2020 Heart Views.)
Databáze: MEDLINE
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