Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil.

Autor: Chagas DF; Universidade Federal do Espirito Santo, Hospital Universitário Cassiano Antônio Morais, Serviço de Dermatologia, Vitória, ES, Brasil., Diniz LM; Universidade Federal do Espirito Santo, Hospital Universitário Cassiano Antônio Morais, Serviço de Dermatologia, Vitória, ES, Brasil., Lucas EA; Universidade Federal do Espirito Santo, Hospital Universitário Cassiano Antônio Morais, Serviço de Dermatologia, Vitória, ES, Brasil., Moraes MO; Fundação Oswaldo Cruz, Serviço de Hansenologia, Rio de Janeiro, RJ, Brasil.
Jazyk: angličtina
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2021 Mar 08; Vol. 54. Date of Electronic Publication: 2021 Mar 08 (Print Publication: 2021).
DOI: 10.1590/0037-8682-0375-2020
Abstrakt: Introduction: Leprosy recurrence is the reappearance of the disease after treatment with current schemes and discharged for cure and may have variable incubation periods.
Methods: This is a descriptive observational study of leprosy recurrence in Espírito Santo diagnosed between January 2018 and January 2020.
Results: One hundred and ninety-two cases were available, of which 30 were diagnosed with leprosy recurrence.
Conclusions: In 25 cases, the incubation period was 5-15 years after the first treatment, favoring bacillary persistence. In the remaining 5 cases, the disease had recurred after 15 years, pointing to reinfection as none of them exhibited drug resistance.
Databáze: MEDLINE