Influence of SARS-CoV-2 during pregnancy: a placental view.

Autor: da Costa MAS; Programa de Pós-graduação em Morfotecnologia, Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil., de Albuquerque Britto DBL; Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil., da Silva ME; Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil., de Carvalho JM; Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil., de Oliveira MLF; Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil., da Silva Gomes JA; Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil., Mendes Tenorio FDCA; Programa de Pós-graduação em Morfotecnologia, Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil., Leite SP; Programa de Pós-graduação em Morfotecnologia, Departamento de Histologia e Embriologia, Universidade Federal de Pernambuco, Recife, Brasil.
Jazyk: angličtina
Zdroj: Biology of reproduction [Biol Reprod] 2021 Jun 04; Vol. 104 (6), pp. 1189-1193.
DOI: 10.1093/biolre/ioab037
Abstrakt: Since the beginning of the current coronavirus outbreak (COVID-19), there has been great concern over a disease that has spread rapidly in several countries worldwide, with the result of several deaths, including deaths of pregnant women. Therefore, the aim of this study was to conduct a literature review on placental changes in infected pregnant women and/or asymptomatic carriers of COVID-19 during pregnancy, aiming at the possible vertical transmission. A systematic collection was carried out on the effects of that COVID-19 can cause directly and/or indirectly to pregnancy and the placenta in the following databases: Pubmed, Science Direct, Scielo, Lilacs, and Web of Science. For search, the following descriptors were used: placenta, pregnant woman, COVID-19, maternal-fetal. The results indicate transplacental transmission in some cases reviewed in many reports from this study. The presence of the virus was seen in the amniotic fluid, umbilical cord, and peripheral blood. Finally, pathological studies suggest that there are morphological changes related to infection in the placentas. We can conclude that, based on the researched material, there is little evidence of transplacental vertical viral transmission and its respective morphological changes related to viral infection in the placenta.
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Databáze: MEDLINE