The effect of diagnostic hysteroscopy performed before fresh and frozen-thawed embryo transfer in IVF cycles on reproductive outcomes

Autor: Eserol F; Clinic of Obstetrics and Gynecology, Batı Bahat Hospital, İstanbul, Turkey; Department of Obstetrics and Gynecology, İstanbul Yeni Yüzyıl University Faculty of Medicine, İstanbul, Turkey, Göksever Çelik H; Clinic of Obstetrics and Gynecology, University of Health Sciences Turkey, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey, Aytan AN; Department of Obstetrics and Gynecology, Bahçeşehir University Faculty of Medicine, İstanbul, Turkey, Çelik A; Clinic of Obstetrics and Gynecology, Batı Bahat Hospital, İstanbul, Turkey, Çelik E; Clinic of Obstetrics and Gynecology, University of Health Sciences Turkey, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey, Buyru F; Department of Obstetrics and Gynecology, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey, Bastu E; Department of Obstetrics and Gynecology, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey
Jazyk: angličtina
Zdroj: Journal of the Turkish German Gynecological Association [J Turk Ger Gynecol Assoc] 2021 Aug 31; Vol. 22 (3), pp. 206-211. Date of Electronic Publication: 2021 Mar 05.
DOI: 10.4274/jtgga.galenos.2021.2020.0136
Abstrakt: Objective: Hysteroscopy is frequently performed in infertile women and thought to improve pregnancy rates. The data obtained from studies investigating the effect of hysteroscopy in in-vitro fertilization (IVF) cycles is variable. We aimed to evaluate the effect of hysteroscopy on pregnancy outcomes of fresh and frozen-thawed embryo transfers (FET) performed during IVF cycles.
Material and Methods: The data of the 765 patients, who had IVF treatment between January 2015 and July 2017 in an infertility center, were retrospectively analyzed. Of those, 586 (76.6%) patients underwent fresh embryo transfer, while 179 (23.4%) patients underwent FET. Hysteroscopy performed by a single experienced surgeon was scheduled two months before transfer. Hysteroscopy was performed in 101/586 (17.2%) in those undergoing fresh embryo transfer and 44/179 (24.6%) patients in the FET group. Pregnancy outcomes of the groups were compared respectively within their own group.
Results: The mean age was similar in patients in the fresh and FET groups (p=0.365, respectively). There was no difference in the number of transferred embryos between the groups (p=0.218). In the fresh embryo group there were 246 pregnancies, of which 44 had undergone diagnostic hysteroscopy while 202 had not, (p=0.516) and 79 pregnancies in the FET group, of which 20 had undergone diagnostic hysteroscopy while 59 had not (p=0.711). There was no statistical difference according to pregnancy rate between the groups (p=0.538).
Conclusion: Performing diagnostic hysteroscopy before fresh or FET does not improve the pregnancy rates.
Databáze: MEDLINE
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