Reliability of corticospinal excitability estimates for the vastus lateralis: Practical considerations for lower limb TMS task selection.

Autor: Proessl F; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Beckner ME; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Sinnott AM; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Eagle SR; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., LaGoy AD; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh Medical School, Pittsburgh, PA, USA., Conkright WR; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Canino MC; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Sterczala AJ; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Midhe Ramkumar PP; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Sciavolino BM; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Connaboy C; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Ferrarelli F; Department of Psychiatry, University of Pittsburgh Medical School, Pittsburgh, PA, USA., Germain A; Department of Psychiatry, University of Pittsburgh Medical School, Pittsburgh, PA, USA., Nindl BC; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA., Flanagan SD; Neuromuscular Research Laboratory/Warrior Human Performance Research Center, Department of Sports Medicine and Nutrition University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: Sdf29@pitt.edu.
Jazyk: angličtina
Zdroj: Brain research [Brain Res] 2021 Mar 02; Vol. 1761, pp. 147395. Date of Electronic Publication: 2021 Mar 02.
DOI: 10.1016/j.brainres.2021.147395
Abstrakt: Transcranial magnetic stimulation (TMS) is increasingly used to examine lower extremity corticospinal excitability (CSE) in clinical and sports research. Because CSE is task-specific, there is growing emphasis on the use of ecological tasks. Nevertheless, the comparative reliability of CSE measurements during established (e.g. knee extensions; KE) and more recent ecological (e.g. squats; SQT) lower extremity tasks has received less attention. The aim of this study was to compare the test-retest reliability of CSE, force, and muscle activity (EMG) during isometric SQT and KE. 19 right-footed men (age: 25 ± 5 yrs) with similar fitness and body composition performed SQT (N = 7) or KE (N = 12) on two consecutive days. Force and EMG were recorded during maximum voluntary isometric contractions (MVC). Corticospinal excitability was determined in the dominant leg during light (15% MVC) contractions based on motor evoked potential (MEP) stimulus-response-curves (SRC). Test-retest reliability, absolute agreement, and consistency were determined for force, EMG, and SRC MEP maximum (MEP MAX ) and rising phase midpoint (V50). As a secondary analysis, all outcomes were compared between groups with mixed-methods ANCOVAs (Task × Time, covariate: body-fat-percentage). Compared with SQT, KE displayed better test-retest reliability and agreement for MEP MAX whereas V50, force, and EMG were similarly reliable. Force (p = 0.01) and MEP MAX (p = 0.02) were also greater during KE despite a similar V50 (p = 0.11). Differences in test-retest reliability, absolute agreement, and between-group comparisons highlight the need to carefully select lower limb TMS assessment tasks and encourage future efforts to balance ecological validity with statistical sensitivity.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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