| Autor: |
de Matos CJ; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil., Schabo DC; Federal Institute of Education, Science and Technology of Rondônia, Colorado do Oeste, Brazil., do Nascimento YM; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil., Tavares JF; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil., Lima EO; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil., da Cruz PO; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil., de Souza EL; Department of Nutrition, Federal University of Paraíba, João Pessoa, Brazil., Magnani M; Department of Food Engineering, Federal University of Paraíba, João Pessoa, Brazil., Magalhães HIF; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil. |
| Abstrakt: |
Contamination of goat milk with aflatoxin M 1 (AFM 1 ) is a public health concern. This study investigated filamentous fungi in goat feed and quantified AFM 1 in milk samples (n = 108) from goat fed forage and concentrate. Based on the detected AFM 1 concentration, risk assessment analyses were performed concerning the Estimated Daily Intake (EDI) for one-year-old children and adults. Filamentous fungi were found in goat feed samples in a range of 3.1 ± 1.9 to 4.2 ± 0.2 log CFU/g. Five genera were identified, to cite Aspergillus, Penicillium, Fusarium, Rhizopus and Acremonium. Aspergillus species comprised A. flavus, A. niger, and A. ochraceus . All goat milk samples were contaminated with AFM 1 (5.60-48.20 ng/L; mean 21.90 ± 10.28 ng/L) in amounts below the limits imposed by regulatory agencies. However, EDI values for AFM 1 through goat milk estimated for one-year-old children were above the Tolerable Daily Intake. The calculated Hazard Index for one-year-old children indicated potential risk of liver cancer due to goat milk consumption. The Margin of Exposure values to AFM 1 in one-year-old children and adults consuming goat milk as the unique milk source indicated increased health risk. Therefore, contamination of goat milk with AFM 1 should be considered a high priority for Brazil's risk management actions. |
