Providers' perspectives on the clinical utility of pharmacogenomic testing in pediatric patients.

Autor: Liko I; Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA.; Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA., Lee YM; Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA., Stutzman DL; Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA.; Department of Pharmacy, Children's Hospital Colorado, Aurora, CO 80045, USA.; Pediatric Mental Health Institute, Children's Hospital Colorado, Aurora, CO 80045, USA., Blackmer AB; Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA.; Department of Pharmacy, Children's Hospital Colorado, Aurora, CO 80045, USA.; Special Care Clinic, Children's Hospital Colorado, Aurora, CO 80045, USA., Deininger KM; Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA., Reynolds AM; Special Care Clinic, Children's Hospital Colorado, Aurora, CO 80045, USA.; Department of Pediatrics, University of Colorado School of Medicine & Children's Hospital Colorado, Aurora, CO 80045, USA., Aquilante CL; Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences, Aurora, CO 80045, USA.
Jazyk: angličtina
Zdroj: Pharmacogenomics [Pharmacogenomics] 2021 Apr; Vol. 22 (5), pp. 263-274. Date of Electronic Publication: 2021 Mar 04.
DOI: 10.2217/pgs-2020-0112
Abstrakt: Aim: To assess providers' knowledge, attitudes, perceptions, and experiences related to pharmacogenomic (PGx) testing in pediatric patients. Materials & methods: An electronic survey was sent to multidisciplinary healthcare providers at a pediatric hospital. Results: Of 261 respondents, 71.3% were slightly or not at all familiar with PGx, despite 50.2% reporting prior PGx education or training. Most providers, apart from psychiatry, perceived PGx to be at least moderately useful to inform clinical decisions. However, only 26.4% of providers had recent PGx testing experience. Unfamiliarity with PGx and uncertainty about the clinical value of testing were common perceived challenges. Conclusion: Low PGx familiarity among pediatric providers suggests additional education and electronic resources are needed for PGx examples in which data support testing in children.
Databáze: MEDLINE