| Autor: |
Chen Z; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China. aimeiyang@163.com., Nie XD, Sun JT, Yang AM, Wei BG |
| Jazyk: |
angličtina |
| Zdroj: |
Organic & biomolecular chemistry [Org Biomol Chem] 2021 Mar 21; Vol. 19 (11), pp. 2492-2501. Date of Electronic Publication: 2021 Mar 03. |
| DOI: |
10.1039/d0ob02603d |
| Abstrakt: |
The Zn(OTf) 2 -catalyzed hydroamination of ynamides 2a-2l with aromatic amines 1a-1r was developed. This protocol features broad substrate scope of aromatic amines, good functional group tolerance for ynamides, and excellent regioselectivities. As a result, a variety of substituted amidine compounds 3aa-3oa, 3ab-3al and 3pa-3rk were prepared in moderate to excellent yields and with high regioselectivities. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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