Antiplatelet Drugs for Neurointerventions: Part 2 Clinical Applications.

Autor: Pearce S; Department of Radiology, Western Health, 160 Gordon St, 3011, Footscray, Victoria, Australia. s.pearce89@gmail.com.; Interventional Neuroradiology Unit, Monash Imaging, Monash Health, Melbourne, Victoria, Australia. s.pearce89@gmail.com., Maingard JT; Interventional Neuroradiology Unit, Monash Imaging, Monash Health, Melbourne, Victoria, Australia.; School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria, Australia., Kuan Kok H; School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria, Australia.; Interventional Radiology Service, Northern Health Radiology, Melbourne, Victoria, Australia., Barras CD; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia., Russell JH; Department of Neurosurgery, Austin Health, Melbourne, Victoria, Australia., Hirsch JA; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Chandra RV; Interventional Neuroradiology Unit, Monash Imaging, Monash Health, Melbourne, Victoria, Australia.; Department of Imaging, Monash University, Melbourne, Victoria, Australia., Jhamb A; Interventional Neuroradiology, St Vincent's Hospital, Melbourne, Victoria, Australia., Thijs V; Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.; School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Department of Neurology, Austin Health, Melbourne, Victoria, Australia., Brooks M; School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria, Australia.; Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.; School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Interventional Neuroradiology service, Radiology Department, Austin Health, Melbourne, Victoria, Australia., Asadi H; Interventional Neuroradiology Unit, Monash Imaging, Monash Health, Melbourne, Victoria, Australia.; School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria, Australia.; Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.; School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Interventional Neuroradiology service, Radiology Department, Austin Health, Melbourne, Victoria, Australia.
Jazyk: angličtina
Zdroj: Clinical neuroradiology [Clin Neuroradiol] 2021 Sep; Vol. 31 (3), pp. 545-558. Date of Electronic Publication: 2021 Mar 01.
DOI: 10.1007/s00062-021-00997-4
Abstrakt: Endovascular techniques have expanded to include balloon and stent-assistance, flow diversion and individualized endovascular occlusion devices, to widen the treatment spectrum for more complex aneurysm morphologies. While usually well-tolerated by patients, endovascular treatment of intracranial aneurysms carries the risk of complications, with procedure-related ischemic complications being the most common. Several antiplatelet agents have been studied in a neurointerventional setting for both prophylaxis and in the setting of intraprocedural thrombotic complications. Knowledge of these antiplatelet agents, evidence for their use and common dosages is important for the practicing neurointerventionist to ensure the proper application of these agents.Part one of this two-part review focused on basic platelet physiology, pharmacology of common antiplatelet medications and future directions and therapies. Part two focuses on clinical applications and evidence based therapeutic regimens.
(© 2021. Springer-Verlag GmbH, DE part of Springer Nature.)
Databáze: MEDLINE
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