Is Spontaneous Pneumomediastinum a Poor Prognostic Factor in Covid-19?

Autor: Ozsoy IE; Department of Thoracic Surgery, Kayseri Health Practice and Research Centre, University of Health Sciences, Turkey., Tezcan MA; Department of Thoracic Surgery, Kayseri Health Practice and Research Centre, University of Health Sciences, Turkey., Guzeldag S; Department of Intensive Care Unit, Kayseri Health Practice and Research Centre, University of Health Sciences, Turkey., Ozdemir AT; Department of Infection Diseases, Kayseri Health Practice and Research Centre, University of Health Sciences, Turkey.
Jazyk: angličtina
Zdroj: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2021 Feb; Vol. 31 (2), pp. 132-137.
DOI: 10.29271/jcpsp.2021.02.132
Abstrakt: Objective: To determine the risk factors for spontaneous pneumomediastinum (SPM), its clinical course and effect on prognosis in patients with Coronavirus disease-19 (COVID-19) pneumonia.
Study Design: Descriptive study.
Place and Duration of Study: Kayseri City Training and Research Hospital, Turkey, from April  to September 2020.
Methodology: All COVID-19 patients' clinical, laboratory, and radiologic characteristics, as well as treatment outcome data, were obtained through medical record extraction. Group A had 50 patients (22 men and 28 women) without SPM, and Group B had 20 patients (10 men and 10 women) with SPM.
Results: Considering the accompanying comorbidities, the frequencies of asthma and inhaler-use was significantly higher in Group B than in Group A (p <0.05). In the CT evaluation at presentation, the rate of involvement of all five lobes of the lung in Group B was significantly higher than in Group A. Rates of tube thoracostomy, mechanical ventilator requirement, length of stay in hospital, and exitus were significantly higher in Group B than in Group A (p <0.05).
Conclusion: SPM development in a patient with COVID-19 pneumonia is a sign that the prognosis will not be good, and these patients need a more aggressive treatment. Key Words: Spontaneous pneumomediastinum, COVİD-19, Pneumothorax, Real-time polymerase chain reaction, Subcutaneous emphysema.
Databáze: MEDLINE