The Molecular Basis for Life in Extreme Environments.

Autor: Ando N; Department of Chemistry & Chemical Biology, Cornell University, Ithaca, New York 14853, USA.; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA., Barquera B; Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York 12180, USA; email: royerc@rpi.edu., Bartlett DH; Marine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093-0202, USA., Boyd E; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana 59717, USA., Burnim AA; Department of Chemistry & Chemical Biology, Cornell University, Ithaca, New York 14853, USA., Byer AS; Department of Chemistry & Chemical Biology, Cornell University, Ithaca, New York 14853, USA., Colman D; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana 59717, USA., Gillilan RE; Center for High Energy X-ray Sciences (CHEXS), Ithaca, New York 14853, USA., Gruebele M; Department of Chemistry, University of Illinois, Urbana-Champaign, Illinois 61801, USA.; Department of Physics, University of Illinois, Urbana-Champaign, Illinois 61801, USA.; Center for Biophysics and Quantitative Biology, University of Illinois, Urbana-Champaign, Illinois 61801, USA., Makhatadze G; Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York 12180, USA; email: royerc@rpi.edu., Royer CA; Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York 12180, USA; email: royerc@rpi.edu., Shock E; GEOPIG, School of Earth & Space Exploration, School of Molecular Sciences, Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, Arizona 85287, USA., Wand AJ; Department of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77845, USA.; Department of Chemistry, Texas A&M University, College Station, Texas 77845, USA.; Department of Molecular & Cellular Medicine, Texas A&M University, College Station, Texas 77845, USA., Watkins MB; Department of Chemistry & Chemical Biology, Cornell University, Ithaca, New York 14853, USA.; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.
Jazyk: angličtina
Zdroj: Annual review of biophysics [Annu Rev Biophys] 2021 May 06; Vol. 50, pp. 343-372. Date of Electronic Publication: 2021 Feb 26.
DOI: 10.1146/annurev-biophys-100120-072804
Abstrakt: Sampling and genomic efforts over the past decade have revealed an enormous quantity and diversity of life in Earth's extreme environments. This new knowledge of life on Earth poses the challenge of understandingits molecular basis in such inhospitable conditions, given that such conditions lead to loss of structure and of function in biomolecules from mesophiles. In this review, we discuss the physicochemical properties of extreme environments. We present the state of recent progress in extreme environmental genomics. We then present an overview of our current understanding of the biomolecular adaptation to extreme conditions. As our current and future understanding of biomolecular structure-function relationships in extremophiles requires methodologies adapted to extremes of pressure, temperature, and chemical composition, advances in instrumentation for probing biophysical properties under extreme conditions are presented. Finally, we briefly discuss possible future directions in extreme biophysics.
Databáze: MEDLINE