Increased Intima-Media Thickness of the Ascending Aorta May Predict Neurological Complications Associated with TAVI.

Autor: Bayar N; Antalya Training and Research Hospital, Cardiology Department, University of Health Sciences, Antalya, Turkey. Electronic address: drnerminbayar07@gmail.com., Erkal Z; Antalya Training and Research Hospital, Cardiology Department, University of Health Sciences, Antalya, Turkey., Köklü E; Antalya Training and Research Hospital, Cardiology Department, University of Health Sciences, Antalya, Turkey., Güven R; Emergency Medicine Department, Kanuni Sultan Süleyman Education and Research Hospital, İstanbul, Turkey., Arslan Ş; Antalya Training and Research Hospital, Cardiology Department, University of Health Sciences, Antalya, Turkey.
Jazyk: angličtina
Zdroj: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 May; Vol. 30 (5), pp. 105665. Date of Electronic Publication: 2021 Feb 23.
DOI: 10.1016/j.jstrokecerebrovasdis.2021.105665
Abstrakt: Objectives: Neurological complications associated with transcatheter aortic valve implantation (TAVI) are important due to its morbidity and mortality risks. The purpose of this study was to investigate the importance of the features of the aortic valve and ascending aorta to predict the neurological complications associated with TAVI.
Methods: The patients for whom the heart team decided to perform TAVI were included in the study. In order to assess possible neurological complications, cerebral diffusionweighted magnetic resonance imaging(MRI) was performed pre- and post-operatively. The diameter of the patients' aortic root and ascending aorta, aortic valve scores, intima media thickness of the ascending aorta were measured from their transesophageal echocardiography records.
Results: A total of 108 patients constituted the study population. 31 patients were found to develop a new lesion (MR+) detected on MRI after TAVI, while 76 patients did not have any new lesions (MR-). The groups did not have any significant differences in their aortic valve features and scores. However, AA-IMT was found to be higher in the MR+ group (1.8mm [1.6-2.3] vs 1.4mm [1.2-1.8] interquartile range). The multivariate logistic regression analysis conducted to detect new lesions revealed that AA-IMT led to a significantly increased risk.
Conclusion: The features of the ascending are more important than the demographic characteristics of patients and features of the native valve in predicting new lesions on MRI scans and thus neurological events after TAVI.
Competing Interests: Declaration of Competing Interest The authors have no conflicts of interest to declare.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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