The national trend of the gastric cancer burden in Iran from 1990 to 2017.

Autor: Fattahi N; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Moghaddam SS; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Rezaei N; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Rezaei N; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Fattahi E; Department of internal medicine, Tohid Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran., Moradveisi B; Cancer and Immunology Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran., Roshani S; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.; Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Farzi Y; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Zakaryaei F; Student research committee, Kurdistan University of Medical Sciences, Sanandaj, Iran., Miraki A; Student Research Committee, Kurdistan University of Medical Science, Sanandaj, Iran., Moradi-Lakeh M; Preventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran., Mokdad AH; Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington., Naghavi M; Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington., Farzadfar F; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Jazyk: angličtina
Zdroj: Asia-Pacific journal of clinical oncology [Asia Pac J Clin Oncol] 2022 Apr; Vol. 18 (2), pp. e96-e102. Date of Electronic Publication: 2021 Feb 25.
DOI: 10.1111/ajco.13563
Abstrakt: Introduction: Gastric cancer (GC), the leading cause of cancer mortality, is the third most common cancer in Iran. To our knowledge, there have been few accurate estimates on the burden of GC in Iran. Therefore, as part of the Global Burden of Diseases Study 2017 (GBD 2017), we aimed to study and illustrate the burden of GC and to compare rates by sex and age groups at the national level in Iran from 1990 to 2017.
Methods: We extracted data related to the 1990-2017 period from the GBD study. To report the burden of GC, we used disability adjusted life years (DALYs), mortality, incidence, and prevalence rates in different sex and age groups in Iran during the 1990-2017 period. Decomposition analysis was also performed to evaluate the roots change in incident cases.
Results: At a national level, the age-standardized prevalence rate (ASPR), age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized DALYs rate (ASDR) in 2017 were 22.9 (95% uncertainty interval [UI]: 22.1-23.9), 14.6 (14.1-15.2), 14.9 (14.4-15.4), and 296.8 (286.3-308.7) per 100,000 population, respectively. Over the 1990-2017 period, the average annual percent changes in all of the studied age-standardized rates were negative. Moreover, the male to female sex ratios of all estimates were greater than one. The incidence rate, prevalence rate, and mortality rate slowly began to increase at the age of 50 and reached its highest level among people aged 80 years and over.
Conclusion: The GC age-standardized rates revealed a downward trend from 1990 to 2017. The current study provides comprehensive knowledge about the GC burden in Iran. Therefore, it can help the appropriate allocation of resources for GC to expand preventive programs by reducing exposure to risk factors and Helicobacter pylori infection and by recommending increased consumption of fruits and vegetables. Also, expanding GC screening programs with laboratory tests or endoscopy can be an important step towards the reduction of the GC burden.
(© 2021 John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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