Comparison of intraoperative and post-operative 3-T MRI performed at 24-72 h following brain tumour resection in children.

Autor: Avula S; Department of Radiology, Alder Hey Children's NHS Foundation Trust, East Prescot Road, Liverpool, L14 5AB, UK. shivaram.avula@alderhey.nhs.uk., Jaspan T; Department ofRadiology, Nottingham University Hospitals, Derby Road, Nottingham, NG7 2UH, UK., Pizer B; Department of Oncology, Alder Hey Children's NHS Foundation Trust, East Prescot Road, Liverpool, L14 5AB, UK., Pettorini B; Department of Neuro-surgery, Alder Hey Children's NHS Foundation Trust, East Prescot Road, Liverpool, L14 5AB, UK., Garlick D; Department of Radiology, Alder Hey Children's NHS Foundation Trust, East Prescot Road, Liverpool, L14 5AB, UK., Hennigan D; Department of Neuro-surgery, Alder Hey Children's NHS Foundation Trust, East Prescot Road, Liverpool, L14 5AB, UK., Mallucci C; Department of Neuro-surgery, Alder Hey Children's NHS Foundation Trust, East Prescot Road, Liverpool, L14 5AB, UK.
Jazyk: angličtina
Zdroj: Neuroradiology [Neuroradiology] 2021 Aug; Vol. 63 (8), pp. 1367-1376. Date of Electronic Publication: 2021 Feb 25.
DOI: 10.1007/s00234-021-02671-5
Abstrakt: Purpose: Intraoperative MRI (ioMRI) is a valuable tool aiding paediatric brain tumour resection. There is no published evidence comparing the effectiveness of the final intraoperative MRI and early post-operative (24-72 h) MRI as baseline scans following brain tumour resection. We aimed to evaluate whether the final ioMRI scan could serve as the post-operative baseline scan after paediatric brain tumour resections.
Methods: This prospective study compared the final ioMRI scan with the immediate post-operative MRI scan performed 24-72 h post-surgery. We included 20 patients aged 6.6-21 years undergoing brain tumour resection using ioMRI and were suitable for MRI scan without general anaesthesia. The scans were independently evaluated by experienced local and external paediatric neuroradiologists. Identical sequences in the final ioMRI and the 24-72-h MRI were compared to assess the extent of resection, imaging characteristics of residual tumour, the surgical field, extent of surgically induced contrast enhancement, and diffusion abnormalities.
Results: In 20 patients undergoing intraoperative and early post-operative MRI, there was no difference between ioMRI and 24-72-h post-op scans in identifying residual tumour. Surgically induced contrast enhancement was similar in both groups. There were more abnormalities on diffusion imaging and a greater degree of oedema around the surgical cavity on the 24-72-h scan.
Conclusion: The final 3-T ioMRI scan may be used as a baseline post-operative scan provided standard imaging guidelines are followed and is evaluated jointly by the operating neurosurgeon and neuroradiologist. Advantages of final ioMRI as a baseline scan are identified.
(© 2021. Crown.)
Databáze: MEDLINE
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