Preference for Easyhaler ® Over Previous Dry Powder Inhalers in Asthma Patients: Results of the DPI PREFER Observational Study.

Autor: Alvarez-Gutiérrez FJ; Unidad de Asma, Hospital Universitario Virgen del Rocio, Sevilla, Spain., Gómez-Bastero Fernández A; Unidad de Asma, Hospital Universitario Virgen Macarena, Sevilla, Spain., Medina Gallardo JF; Unidad de Asma, Hospital Universitario Virgen del Rocio, Sevilla, Spain., Campo Sien C; Orion Pharma Iberia, Madrid, Spain., Rytilä P; Orion Pharma Corporate, Espoo, Finlandia., Delgado Romero J; Unidad de Gestión Clinica Alergología, Hospital Virgen Macarena, Sevilla, Spain.
Jazyk: angličtina
Zdroj: Patient preference and adherence [Patient Prefer Adherence] 2021 Feb 16; Vol. 15, pp. 349-358. Date of Electronic Publication: 2021 Feb 16 (Print Publication: 2021).
DOI: 10.2147/PPA.S295710
Abstrakt: Objective: To study patient preference for and satisfaction with the Easyhaler ® device and to assess ease of training and use of the inhaler in patients previously treated with a variety of dry powder inhalers (DPIs).
Methods: We designed a non-interventional, cross-sectional, single-visit observational study of adult patients with persistent asthma referred to specialized care who had previously been treated with DPI inhalers for at least 3 months. Once clinical baseline data had been checked, patients filled in questionnaires on asthma control (GINA 2019), Feeling of Satisfaction with the Inhaler (FSI-10), and adherence (TAI and Morisky-Green questionnaires). Thereafter, all patients were trained in the use of Easyhaler. We assessed ease of use and satisfaction (FSI-10) with Easyhaler, as well as inhaler device preferences.
Results: We recruited 502 patients (mean age, 50.2 ± 16.2 y; 63.1% female), of whom 485 were evaluable. In response to the main objective of the study, we compared the values of the self-completed adapted FSI-10, to measure satisfaction with the inhaler. A significantly higher score in each item of the questionnaire was recorded for Easyhaler. Overall, 38% of patients showed exclusive preference for Easyhaler (compared with 15% for the previous device) or were evenly matched in 46% of cases.
Conclusion: In the present study, Easyhaler achieved better patient ratings in terms of preference and satisfaction than previously used DPI devices. In order to improve asthma adherence strategies, patient preferences and device choice should be taken into account.
Competing Interests: FJAG has received fees for consultancy, lectures or attendance to congresses and scientific meetings from ALK-Abelló, AstraZeneca, Bial, Boehringer- Ingelheim, Chiesi, GSK, Menarini, Mundipharma, Novartis, Orion Pharma, Sanofi-Genzyme and TEVA. AGBF has received fees for consultancy, lectures or attendance to congresses and scientific meetings from ALK-Abelló, AstraZeneca, Bial, Chiesi, GSK, Menarini, Mundipharma, Novartis, Orion Pharma, Sanofi-Genzyme and TEVA. JFMG has received fees for consultancy, lectures or attendance to congresses and scientific meetings from ALK-Abelló, AstraZeneca, Bial, Chiesi, GSK, Novartis, Orion Pharma y Sanofi-Genzyme. CCS and PR are employees of Orion Pharma. JDR has received fees for consultancy or lectures from GSK, Astra, Sanofi-Genzyme, TEVA, Orion Pharma, Bial, Novartis, and Leti. The authors report no other conflicts of interest in this work.
(© 2021 Alvarez-Gutiérrez et al.)
Databáze: MEDLINE