Optimizing Multivitamin Supplementation for Sleeve Gastrectomy Patients.

Autor: Heusschen L; Department of Bariatric Surgery, Vitalys, part of Rijnstate Hospital, PO box 9555, 6800, Arnhem, The Netherlands. LHeusschen@Rijnstate.nl.; Divison of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands. LHeusschen@Rijnstate.nl., Berendsen AAM; Divison of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands., Cooiman MI; Department of Bariatric Surgery, Vitalys, part of Rijnstate Hospital, PO box 9555, 6800, Arnhem, The Netherlands., Deden LN; Department of Bariatric Surgery, Vitalys, part of Rijnstate Hospital, PO box 9555, 6800, Arnhem, The Netherlands., Hazebroek EJ; Department of Bariatric Surgery, Vitalys, part of Rijnstate Hospital, PO box 9555, 6800, Arnhem, The Netherlands.; Divison of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands., Aarts EO; Department of Bariatric Surgery, Vitalys, part of Rijnstate Hospital, PO box 9555, 6800, Arnhem, The Netherlands.
Jazyk: angličtina
Zdroj: Obesity surgery [Obes Surg] 2021 Jun; Vol. 31 (6), pp. 2520-2528. Date of Electronic Publication: 2021 Feb 23.
DOI: 10.1007/s11695-021-05282-4
Abstrakt: Purpose: Micronutrient deficiencies are frequently reported after sleeve gastrectomy (SG), and therefore lifelong daily multivitamin supplementation is highly recommended. Based on literature and the results of a previous randomized controlled trial, a specialized multivitamin supplement for SG patients was further optimized (WLS Optimum 2.0, FitForMe). The present study reports on its short-term effectiveness.
Materials and Methods: An open-label study was performed in which 76 patients were included to receive WLS Optimum 2.0 for 12 months (Opt 2.0 group). This group was compared with a group of 75 patients that had received WLS Optimum 1.0 for 12 months during a previous study (Opt 1.0 group).
Results: Intention-to-treat analysis (Opt 1.0, n = 69; Opt 2.0, n = 75) showed higher serum levels of vitamin B12, vitamin B6, and zinc, and a lower prevalence of deficiencies for vitamin B12 and phosphate in the Opt 2.0 group. MCV and serum folic acid levels were higher in the Opt 1.0 group. Over the 12-month study period, mean increase in serum levels of phosphate, vitamin B6, and zinc was higher in the Opt 2.0 group, and MCV and serum vitamin D levels increased more in the Opt 1.0 group.
Conclusion: The present study showed that the use of a specialized multivitamin supplement for SG patients is effective at preventing deficiencies for most vitamins and minerals, specifically in compliant patients. However, a strict follow-up regime remains necessary to monitor nutritional status and to improve patient compliance.
Databáze: MEDLINE
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