[Cross-sectional study of the clinical characteristics and outcomes of children hospitalized with COVID-19 in Lima, Peru].

Autor:	Domínguez Rojas J; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. Adress: Fray Angélico 238 Departamento 103, San Borja, Lima, Perú. Email: jesusdominguez24@gmail.com. ORCID: 0000-0001-6141-6622., Estupiñan Vigil M; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. ORCID: 0000-0002-4226-7729., Garcés-Ghilardi R; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. ORCID: 0000-0001-8813-8650., Alvarado-Gamarra G; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. ORCID: 0000-0002-7266-5808., Del Águila O; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú. ORCID: 0000-0003-3085-0148., Lope Tenorio AF; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Ricardo Palma, Lima, Perú. ORCID: 0000-0002-9071-2428., Ayón Dejo CC; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú. ORCID: 0000-0003-2787-2581., Chonlon Murillo K; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. ORCID: 0000-0002-6813-2902., Boluarte Baca S; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad San Martin de Porres, Lima, Perú. ORCID: 0000-0001-8270-8982., Stapleton Herbozo A; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Ricardo Palma, Lima, Perú. ORCID: 0000-0002-8019-6247., Seminario Aliaga R; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. ORCID: 0000-0003-3131-4881., Reyes Florian G; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Ricardo Palma, Lima, Perú. ORCID: 0000-0003-4855-9033., Dávila Riega D; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. ORCID: 0000-0003-1085-1274., Fernández Suárez S; Departamento de Pediatría, Hospital Edgardo Rebagliati Martins, Lima, Perú; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú. ORCID: 0000-0003-1345-8726., Coronado Muñoz Á; Departamento de Pediatría, Centro de Ciencias de la Salud de la Universidad de Texas en Houston, Estados Unidos. ORCID: 0000-0001-5349-5260.
Jazyk:	Spanish; Castilian
Zdroj:	Medwave [Medwave] 2021 Jan 20; Vol. 21 (1), pp. e8107. Date of Electronic Publication: 2021 Jan 20.
DOI:	10.5867/medwave.2021.01.8107
Abstrakt:	Introduction: Coronavirus 2019 (SARS-CoV-2) infection in children occurred in Peru as of March 2020, leading to pediatric patients' hospitalization in areas adapted for this purpose at the Edgardo Rebagliati Martins National Hospital. In the beginning, the demand for hospitalization was low, but it increased gradually. Consistent with international reports, the majority of patients presented mild or moderate symptoms. Nonetheless, there were also severe cases, even fatal ones. Objectives: To describe the characteristics and clinical outcome of pediatric patients with COVID-19 hospitalized in a referral hospital in Lima, Peru, between March and August 2020. Methods: A descriptive and inferential cross-sectional study was carried out. The population includes all hospitalized patients in the Department of Pediatrics, with clinical and surgical diagnoses associated with COVID-19. Results: We included 100 patients, with an average age of 83.4 ± 54 months, with a predominance of male patients (55%). Hospitalized patients were grouped into five categories: respiratory failure (17%), multisystemic inflammatory syndrome (MIS-C) (31%), neurological presentation (19%), acute abdomen (20%), and patients with oncological problems (13%). Most of the patients (74%) had comorbidities. Regarding the presenting symptoms, intestinal pain predominated in the appendicitis group (90%, p < 0.001), fever was present in most patients with respiratory failure (64.7%); multisystemic inflammatory syndrome (90.3%), neurological manifestations (15.8%), acute abdomen (50%) and oncological conditions (61.5%) were also present in these patients. Kawasaki symptoms were found in 38.7% of the patients with multisystemic inflammatory syndrome. Mortality was 4%. Respiratory problems (29.4%) and multisystemic inflammatory syndrome (22.6%) required admission to intensive care, more frequently than the other presentations (p = 0.008). Conclusions: We conclude that the vulnerability in the pediatric population is the one that has preexisting conditions. We divided our patients according to presentation, diagnosis, and complications, which were predominantly respiratory. We also had oncological patients with COVID-19.
Databáze:	MEDLINE
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