Clinical correlation and antimicrobial susceptibility pattern of Chryseobacterium spp.: A three year prospective study.

Autor:	Yadav VS; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Das BK; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Mohapatra S; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Ahmed MN; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Gautam H; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Kapil A; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Sood S; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Dhawan B; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India., Chaudhry R; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Jazyk:	angličtina
Zdroj:	Intractable & rare diseases research [Intractable Rare Dis Res] 2021 Feb; Vol. 10 (1), pp. 37-41.
DOI:	10.5582/irdr.2020.03085
Abstrakt:	Chryseobacterium species are widely distributed in the environment. They are rarely found in hospital settings causing nosocomial infections. Limited data is available regarding their epidemiology, clinical significance and antimicrobial susceptibility patterns. This study was aimed to identify different species of Chryseobacterium using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) and to correlate clinically with antimicrobial susceptibility patterns in a tertiary care hospital in north India. We also performed phenotypic tests, which may be useful to differentiate this bacterium from other non-fermenters. A total of 20 isolates of Chryseobacterium spp. were identified over a period of 3 years. Chryseobacterium indologenes (18/20) was the most common species isolated followed by Chryseobacterium gleum (2/20) from various clinical samples. Antimicrobial susceptibility testing (AST) was performed. Susceptibility to rifampicin was observed at a maximum (75%) followed by piperacillin-tazobactum (45%). Susceptibility against imipenem, meropenem, cotrimoxazole and cefoperazone-sulbactum were observed approximately 33%. Amikacin, cefotaxime and ceftazidime showed least susceptibility results. Further clinical correlation was established. Competing Interests: The authors have no conflicts of interest to disclose. (2021, International Research and Cooperation Association for Bio & Socio - Sciences Advancement.)
Databáze:	MEDLINE
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