An Atypical Presentation of Lemierre's Syndrome: Complicated by Thrombotic Thrombocytopenic Purpura.
| Autor: | Vera Nieves B; Infectious Disease, Aventura Hospital and Medical Center, Miami, USA., Lindblad G; Radiology, Aventura Hospital and Medical Center, Miami, USA., Gupta J; Internal Medicine, Aventura Hospital and Medical Center, Miami, USA., Hughes J; Internal Medicine, Aventura Hospital and Medical Center, Miami, USA., Rivero A; Infectious Disease, Aventura Hospital and Medical Center, Miami, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2021 Jan 15; Vol. 13 (1), pp. e12728. Date of Electronic Publication: 2021 Jan 15. |
| DOI: | 10.7759/cureus.12728 |
| Abstrakt: | Lemierre's syndrome is an oropharyngeal infection complicated by septic thrombophlebitis of the internal jugular vein, bacteremia, and septic emboli. It mainly occurs in immunocompetent individuals and was first reported in the early 1900s by physician Andre Lemierre. A 23-year-old male presented to our institution with sore throat, difficulty swallowing, left-sided ear pain, nausea, vomiting, subjective fevers, general malaise, right-sided rib pain, and anorexia. Complete blood cell count and metabolic panels revealed severe thrombocytopenia, mild anemia, acute kidney injury, and hyperbilirubinemia. Blood cultures grew Fusobacterium necrophorum . Ultrasound and computed tomography scan of the neck revealed thrombosis of the left internal jugular vein. ADAMTS13 activity was later reported to be markedly decreased at less than 2%, confirming a diagnosis of thrombotic thrombocytopenic purpura. Competing Interests: This research was supported (in whole or in part) by HCA Healthcare and/or an HCA Healthcare-affiliated entity. The views expressed in this publication represent those of the author(s) and do not necessarily represent the official views of HCA Healthcare or any of its affiliated entities. (Copyright © 2021, Vera Nieves et al.) |
| Databáze: | MEDLINE |
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