Effects of resistance training and nigella sativa on type 2 diabetes: implications for metabolic markers, low-grade inflammation and liver enzyme production.

Autor: Jangjo-Borazjani S; Department of Physical Education and Sport Sciences, Bushehr Branch, Islamic Azad University, Bushehr, Iran., Dastgheib M; Department of Physical Education and Sport Sciences, Bushehr Branch, Islamic Azad University, Bushehr, Iran., Kiyamarsi E; Department of Physical Education and Sport Sciences, Bushehr Branch, Islamic Azad University, Bushehr, Iran., Jamshidi R; Department of Physical Education and Sport Sciences, Bushehr Branch, Islamic Azad University, Bushehr, Iran., Rahmati-Ahmadabad S; Department of Physical Education, Pardis Branch, Islamic Azad University, Pardis, Iran., Helalizadeh M; Department of Exercise Physiology, Sport Medicine Research Center, Sport Sciences Research Institute, Tehran, Iran., Iraji R; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Canada., Cornish SM; Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Canada., Mohammadi-Darestani S; Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran., Khojasteh Z; Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran., Azarbayjani MA; Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Jazyk: angličtina
Zdroj: Archives of physiology and biochemistry [Arch Physiol Biochem] 2023 Dec; Vol. 129 (4), pp. 913-921. Date of Electronic Publication: 2021 Feb 21.
DOI: 10.1080/13813455.2021.1886117
Abstrakt: Context: Proper nutrition and exercise are effective strategies to improve overall metabolic health in diabetic patients.
Objective: This study evaluated the effects of Nigella sativa (NS) supplementation during resistance training (RT) on some biochemical variables in type 2 diabetes patients.
Methods: Forty patients were assigned to groups: RT + NS (RN), NS, RT + placebo (RP), and control (CO). RT was performed and NS was consumed for 8 weeks. Blood samples were collected at rest immediately before and after the 8 week intervention.
Results: RT or NS by themselves reduced HOMA-IR, insulin, glucose, TG, TC, LDL, ESR, CRP, AST, ALT and ALP, and increased HDL and HOMA-S. The combination of RT and NS, rather than each intervention alone, had significant effects on reduction of HOMA-IR, insulin, ESR and CRP as well as increases in HDL, HOMA-β/S.
Conclusion: RT combined with NS is sometimes a better strategy compared to single interventions for improving diabetes related biomarkers in type 2 diabetic patients.
Databáze: MEDLINE
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