| Autor: |
Soler MC; Servicio de Emergentología, Hospital Interzonal General de Agudos San Martín, La Plata, Buenos Aires, Argentina. E-mail: mercedescsoler@gmail.com., Mogliani S; Servicio de Emergentología, Hospital Interzonal General de Agudos San Martín, La Plata, Buenos Aires, Argentina., Benítez ST; Servicio de Emergentología, Hospital Interzonal General de Agudos San Martín, La Plata, Buenos Aires, Argentina., Cabillón LN; Servicio de Emergentología, Hospital Interzonal General de Agudos San Martín, La Plata, Buenos Aires, Argentina., Rollié RD; Servicio de Emergentología, Hospital Interzonal General de Agudos San Martín, La Plata, Buenos Aires, Argentina., Martins GM; Servicio de Emergentología, Hospital Interzonal General de Agudos San Martín, La Plata, Buenos Aires, Argentina. |
| Abstrakt: |
We present the clinical cases of two patients who were admitted to the HIGA San Martín de La Plata emergency ward with a clinical picture compatible with leptospirosis, who evolved with respiratory failure and alveolar hemorrhage. In both, glucocorticoids were administered with good evolution. A bibliographic search of articles published since 2005 in Spanish and English and a review of the topic was carried out. Based on the current evidence, no clear recommendation can be made for the use of corticosteroids in severe leptospirosis. The published bibliography is scarce and of low quality. There would appear to be a benefit in the use of corticosteroids in cases of pulmonary involvement due to severe leptospirosis. High-quality studies are needed to make recommendations with scientific evidence, to verify the adequate dose of corticosteroids, time of initiation, duration of treatment and the cases in which this therapy should be administered. |
