Will allogeneic CAR T cells for CD19 + malignancies take autologous CAR T cells 'off the shelf'?

Autor: DiNofia AM; Cancer Immunotherapy Program, Cellular Therapy and Transplant Section, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Oncology, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Grupp SA; Cancer Immunotherapy Program, Cellular Therapy and Transplant Section, Children's Hospital of Philadelphia, Philadelphia, PA, USA. grupp@chop.edu.; Division of Oncology, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. grupp@chop.edu.
Jazyk: angličtina
Zdroj: Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2021 Apr; Vol. 18 (4), pp. 195-196.
DOI: 10.1038/s41571-021-00485-1
Databáze: MEDLINE