Neurological growth and development of children asymptomatic at birth whose mothers had Zika during pregnancy.

Autor:	Maia AMPC; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil.; Secretaria de Saúde do Município de Fortaleza, Fortaleza, CE, Brasil., Azevedo CSL; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil.; Secretaria de Saúde do Município de Fortaleza, Fortaleza, CE, Brasil., Oliveira RMAB; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil., Barreto FKA; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil., Rodrigues ASR; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil., Simião AR; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil.; Secretaria de Saúde do Estado do Ceará, Fortaleza, CE, Brasil., Gomes IP; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil., Ribeiro EM; Hospital Infantil Albert Sabin, Fortaleza, CE, Brasil.; Centro Universitário Christus, Faculdade de Medicina, Fortaleza, CE, Brasil., Cavalcanti LPG; Universidade Federal do Ceará, Programa de Pós-graduação em Saúde Coletiva, Fortaleza, CE, Brasil.; Centro Universitário Christus, Faculdade de Medicina, Fortaleza, CE, Brasil.; Universidade Federal do Ceará, Programa de Pós-graduação em Patologia, Fortaleza, CE, Brasil.
Jazyk:	angličtina
Zdroj:	Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2021 Feb 10; Vol. 54, pp. e01802020. Date of Electronic Publication: 2021 Feb 10 (Print Publication: 2021).
DOI:	10.1590/0037-8682-0180-2020
Abstrakt:	Introduction: Newborn who had Zika vírus but did not show microcephaly at birth may have neuropsychomotor development problems. We aimed to evaluate the developmental and anthropometric milestones of asymptomatic children whose mothers had Zika during pregnancy in Northeastern Brazil in 2015 and 2016. Methods: We conducted a descriptive cross-sectional case series study of children in Fortaleza born without microcephaly whose mothers had Zika during pregnancy. Home visits were undertaken to evaluate the developmental milestones and gather anthropometric data of the children and to conduct semi-structured interviews with the mothers to identify their socioeconomic and gestational profiles and assess the newborns after birth. Results: In total, 30 cases were identified. Of these, 17 children and their mothers participated in the study. The median age of the mothers at the time of delivery was 26 years. All were symptomatic, and TORCH was negative. At the time of the home visit, all had growth profiles suitable for their age. However, nearly all children (15/17, 88.2%) presented at least one developmental delay, considering their age group. Conclusions: There were late changes in the neuropsychomotor development of children born to mothers who had Zika during pregnancy, suggesting the need for specialized medical follow-ups.
Databáze:	MEDLINE
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