| Autor: |
Dosoky WM; Department of Animal and Fish Production, Faculty of Agriculture Saba Basha, University of Alexandria, Alexandria, 21531, Egypt., Fouda MMG; Pre-Treatment and Finishing of Cellulosic Fabric Department, Textile Industries Research Division, National Research Center, 33 El-Behooth St., Dokki, Giza, 12311, Egypt. m_gaballa@yahoo.com., Alwan AB; Agricultural Botany Department, Faculty of Agriculture, Alexandria University, Saba Basha, 21531, Egypt., Abdelsalam NR; Agricultural Botany Department, Faculty of Agriculture, Alexandria University, Saba Basha, 21531, Egypt. nader.wheat@alexu.edu.eg., Taha AE; Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Edfina, 22758, Egypt., Ghareeb RY; Plant Protection and Biomolecular Diagnosis Department, Arid Lands Cultivation Research Institute, The City of Scientific Research and Technological Applications, New Borg El Arab, 21934, Alexandria, Egypt., El-Aassar MR; Polymer Materials Research Department, Advanced Technology and New Material Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, 21934, Alexandria, Egypt., Khafaga AF; Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Edfina, 22758, Egypt. asmaa.khafaga@alexu.edu.eg. |
| Abstrakt: |
Silver nanoparticles (AgNPs) have been used as a promising alternative to antibiotics in poultry feed. In this study, silver-doped silica nanoparticles (SiO 2 @AgNPs) were prepared in powder form, using starch, via the chemical reduction method and sol-gel technique followed by full characterization. SiO 2 @AgNPs were added to the poultry diet at three doses (2, 4, and 8 mg/kg diet). The safety of the oral dietary supplementation was estimated through the evaluation of the growth performance and hematological, biochemical, and oxidative parameters of birds. Moreover, the immunohistochemical examination of all body organs was also performed. Results of this study showed that SiO 2 @AgNPs have no negative effects on the growth performance and hematological, biochemical, and oxidative parameters of birds. Moreover, the immunohistochemical examination revealed the minimum inflammatory reactions and lymphoid depletion under a dose level of 8 mg/kg. In conclusion, SiO 2 @AgNPs could be considered as a promising and safe nano-growth promoter in broilers when added to poultry diet under a dose level of 4 mg/kg diet. |
