Pregnant patient with extranodal CNS Rosai-Dorfman disease with new-onset seizures: the conundrum of differentiating disease progression from eclampsia.

Autor:	Swor K; Obstetrics-Gynecology, Wayne State University, Detroit, Michigan, USA kswor@med.wayne.edu., Zutshi D; Neurology, Wayne State University, Detroit, Michigan, USA., Dubey E; Emergency Medicine, Wayne State University, Detroit, Michigan, USA., Gonik B; Obstetrics-Gynecology, Wayne State University, Detroit, Michigan, USA.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2021 Feb 18; Vol. 14 (2). Date of Electronic Publication: 2021 Feb 18.
DOI:	10.1136/bcr-2020-239427
Abstrakt:	A 31-year-old woman at 30 weeks gestation presented to the emergency department following multiple seizures. Her history was significant for extranodal Rosai-Dorfman Disease (RDD) with central nervous system (CNS) lesions. RDD, a rare form of non-Langerhans cell histiocytosis, commonly presents with non-tender cervical lymphadenopathy. CNS involvement accounts for a small number of cases in those with extranodal disease. Patients with CNS RDD can have a variety of neurological symptoms, including seizures. Eclampsia, a relatively rare obstetric hypertensive disorder, is always within the differential diagnosis for patients presenting with late gestation seizures. We present the challenging evaluation and treatment of a patient whose clinical picture did not clearly differentiate eclampsia from new onset seizures related to progression of her RDD. This conundrum perhaps resulted in unnecessary preterm operative delivery of a critically ill patient. Only follow-up of the patient helped clarify the likely antepartum diagnosis. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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