Feasibility of Ethyl Glucuronide Nail Testing Biomarker for Alcohol Use Among Youth Living With HIV.

Autor: Budhwani H; Department of Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham (UAB), Birmingham, Alabama. Electronic address: budhwani@uab.edu., Dinaj V; Department of Family Medicine and Public Health Sciences, School of Medicine, Wayne State University, Detroit, Michigan., Jacques-Tiura AJ; Department of Family Medicine and Public Health Sciences, School of Medicine, Wayne State University, Detroit, Michigan., Pennar AL; Department of Family Medicine and Public Health Sciences, School of Medicine, Wayne State University, Detroit, Michigan., Naar S; Center for Translational Behavioral Science, Florida State University College of Medicine, Tallahassee, Florida.
Jazyk: angličtina
Zdroj: The Journal of adolescent health : official publication of the Society for Adolescent Medicine [J Adolesc Health] 2021 Aug; Vol. 69 (2), pp. 346-348. Date of Electronic Publication: 2021 Feb 15.
DOI: 10.1016/j.jadohealth.2020.12.134
Abstrakt: Purpose: We assessed the feasibility of the ethyl glucuronide biomarker (EtG) through nail sampling to measure alcohol use among youth living with HIV in the United States (YLWH, N = 183); we also evaluated concordance between this EtG biomarker and self-reported measures of alcohol use, specifically, the Alcohol Timeline Followback (TFLB) and Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST).
Methods: EtG, TFLB, and ASSIST were collected at 4 points over 1 year. At baseline and 52 weeks, 78.1% and 70.1%, respectively, provided a valid (full or partial) sample.
Results: At 16 weeks, EtG was associated with ASSIST (r = .25, p < .05). At 28 weeks and 52 weeks, TFLB and ASSIST were correlated with EtG (at 28 weeks r = .23, p < .05 and r = .41, p < .01, respectively; at 52 weeks r = .34, p < .01 and r = .25, p < .05, respectively).
Conclusions: We found that nail-based EtG biomarker was feasible to measure alcohol use among YLWH; we also found concordance between EtG, TLFB, and ASSIST, supporting ongoing use of self-reported alcohol use measures with YLWH.
(Copyright © 2021 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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