The histopathological results of vestibulectomy specimens in localized provoked vulvodynia in Turkey.
Autor: | Eserdag S; Hera Clinic, Istanbul, Turkey., Kurban D; Hera Clinic, Ankara, Turkey., Kiseli M; Faculty of Medicine, Ufuk University, Ankara, Turkey., Alan M; Tepecik Educational and Research Hospital, Kazim Dirik District, 35100 Bornova, Izmir, Turkey., Alan Y; Izmir Metropolitan Municipality Esrefpasa Hospital, Izmir, Turkey. |
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Jazyk: | angličtina |
Zdroj: | The Pan African medical journal [Pan Afr Med J] 2020 Nov 24; Vol. 37, pp. 267. Date of Electronic Publication: 2020 Nov 24 (Print Publication: 2020). |
DOI: | 10.11604/pamj.2020.37.267.21240 |
Abstrakt: | Introduction: Localized Provoked Vulvodynia (LPV) is a gynecological disease that is difficult to manage. Despite the wide spectrum of pathophysiological mechanisms and treatment modalities, there is limited success in the management of this disease. Surgical treatment is usually performed as the last resort. We aimed to investigate the histopathological results of 38 women with LPV who underwent surgical vestibulectomy. Methods: of the 55 women that were diagnosed with LPV and underwent vulvar vestibulectomy, 38 patients with complete histopathological results were included in this retrospective study. Results: in 14 patients, the pathological reports revealed Low-Grade Squamous Intraepithelial Lesions (LGSIL) (36.8%) whereas for 21 cases (55.2%), the findings were concordant with vestibulitis. The remaining three patients (7.8%) were diagnosed with lichen simplex chronicus. Conclusion: the presence of LGSIL in the surgical specimens of LPV cases is noteworthy. In this group of patients, surgical excision may contribute to the prevention of progression into high-grade lesions. The relationship between Human Papilloma Virus (HPV) infections and LPV should be further investigated. Competing Interests: The authors declare no competing interests. (Copyright: Suleyman Eserdag et al.) |
Databáze: | MEDLINE |
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