Comparison of prognostic scales for patients with metastatic spine disease.

Autor: Denisov AA; National Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. Petersburg., Zaborovsky NS; National Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. Petersburg., Ptashnikov DA; National Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. Petersburg.; Mechnikov North-Western State Medical University, St. Petersburg, Russian Federation., Mikhailov DA; National Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. Petersburg., Masevnin SV; National Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. Petersburg., Smekalenkov OA; National Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. Petersburg.
Jazyk: angličtina
Zdroj: Orthopedic reviews [Orthop Rev (Pavia)] 2021 Jan 28; Vol. 12 (4), pp. 8822. Date of Electronic Publication: 2021 Jan 28 (Print Publication: 2020).
DOI: 10.4081/or.2020.8822
Abstrakt: This is one-centre retrospective study with the aim to identify the scale, which provides the most accurate prediction of life expectancy in patients with metastatic lesions in spine. A retrospective analysis of clinical data of 138 patients with metastatic spinal tumors. Patients underwent spinal cord decompression and instrumented stabilization of affected area. We evaluated the general condition according to the Karnofsky and ECOG scales, the presence of metastases in the visceral organs, spine and other bones, the neurological status and conduction of the medical therapy before spinal surgery. Observed clinical parameters were converted to Tokuhashi, Tomita, and Katagiri scales. For statistical analysis, software environment R 3.4.1 was used. Assessment of prognostic accuracy was performed using ROC analysis. The Tokuhashi scale showed AUC 0.605 (95% CI 0.586-0.616), Tomita scale showed AUC 0.708 (95% CI 0.573-0.842), Katagiri scale showed AUC 0.650 (95% CI 0.508-0.792). The best results for survival rate predicting after surgical treatment for metastatic spinal lesions were shown the Tomita scale.
Competing Interests: Conflict of interest: The authors declare no conflict of interest.
(©Copyright: the Author(s).)
Databáze: MEDLINE
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