Real-world implementation and impact of a rapid carbapenemase detection test in an area endemic for carbapenem-resistant Enterobacterales.

Autor: Trzebucki AM; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York., Westblade LF; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York., Loo A; Department of Pharmacy, NewYork-Presbyterian Hospital, New York, New York., Mazur S; Department of Pharmacy, NewYork-Presbyterian Hospital, New York, New York., Jenkins SG; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York., Calfee DP; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York.; Department of Infection Prevention and Control, NewYork-Presbyterian Hospital, New York, New York., Satlin MJ; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York., Simon MS; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York.; Department of Infection Prevention and Control, NewYork-Presbyterian Hospital, New York, New York.
Jazyk: angličtina
Zdroj: Infection control and hospital epidemiology [Infect Control Hosp Epidemiol] 2022 Jan; Vol. 43 (1), pp. 92-95. Date of Electronic Publication: 2021 Feb 15.
DOI: 10.1017/ice.2021.6
Abstrakt: A retrospective study was conducted to describe the impact of a molecular assay to detect the most common carbapenemase genes in carbapenem-resistant Enterobacterales isolates recovered in culture. Carbapenemases were detected in 69% of isolates, and assay results guided treatment modifications or epidemiologic investigation in 20% and 4% of cases, respectively.
Databáze: MEDLINE