Are pain, functional limitations and quality of life associated with objectively measured physical activity in patients with end-stage osteoarthritis of the hip or knee?

Autor: Leichtenberg CS; Leiden University Medical Center, Department of Orthopaedics, Leiden, the Netherlands., van Tol FR; Leiden University Medical Center, Department of Orthopaedics, Leiden, the Netherlands., Gademan MGJ; Leiden University Medical Center, Department of Orthopaedics, Leiden, the Netherlands; Leiden University Medical Center, Department of Clinical Epidemiology, Leiden, the Netherlands. Electronic address: M.G.J.gademan@lumc.nl., Krom T; Leiden University Medical Center, Department of Orthopaedics, Leiden, the Netherlands., Tilbury C; Leiden University Medical Center, Department of Orthopaedics, Leiden, the Netherlands., Horemans HLD; Erasmus MC University Medical Center, Department of Rehabilitation Medicine, Rotterdam, the Netherlands., Bussmann JBJ; Erasmus MC University Medical Center, Department of Rehabilitation Medicine, Rotterdam, the Netherlands., Verdegaal SHM; Alrijne Hospital, Department of Orthopaedics, Leiderdorp, the Netherlands., Marijnissen WJCM; Albert Schweitzer Hospital, Department of Orthopaedics, Dordrecht, the Netherlands., Nelissen RGHH; Leiden University Medical Center, Department of Orthopaedics, Leiden, the Netherlands., Vliet Vlieland TPM; Leiden University Medical Center, Department of Orthopaedics, Leiden, the Netherlands; Sophia Rehabilitation Center, The Hague, the Netherlands; Rijnlands Rehabilitation Center, Leiden, the Netherlands.
Jazyk: angličtina
Zdroj: The Knee [Knee] 2021 Mar; Vol. 29, pp. 78-85. Date of Electronic Publication: 2021 Feb 12.
DOI: 10.1016/j.knee.2020.12.019
Abstrakt: Objectives: Physical activity is promoted in patients with hip or knee osteoarthritis (OA), yet little is known about its relationship with symptoms, functional limitations and Quality of Life (QoL). We investigated if OA-associated pain, functional limitations and QoL are associated with objectively measured physical activity in patients with end-stage hip/knee OA.
Methods: Cross-sectional study including patients scheduled for primary total hip/knee arthroplasty. Patients wore an accelerometer (Activ8) with physical activity assessed over waking hours, and expressed as number of activity daily counts (ADC) per hour, %time spent on physical activity i.e. walking, cycling or running (%PA), and %time spent sedentary (%SB). Pain, functional limitations and joint-specific and general QoL were assessed with the Hip disability/Knee Injury and Osteoarthritis Outcome Score (HOOS/KOOS) and the Short Form (SF)-12. Multivariate linear regression models with the three to Z-scores transformed parameters of physical activity as dependent variables and adjusted for confounding, were conducted.
Results: 49 hip and 48 knee OA patients were included. In hip and knee OA patients the mean number of ADC, %PA and %SB were 18.79 ± 7.25 and 21.19 ± 6.16, 14 ± 6.4 and 15 ± 5.0, and 66 ± 10.5 and 68 ± 8.7, respectively. In hip OA, better joint-specific and general QoL were associated with more ADC, (β 0.028; 95%CI:0.007-0.048, β0.041; 95%CI:0.010-0.071). Also, better general QoL was associated with the %PA (β 0.040, 95%CI:0.007-0.073). No other associations were found.
Conclusion: Whereas QoL was associated with physical activity in hip OA, pain and functional limitations were not related to objectively measured physical activity in patients with end-stage hip or knee OA.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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