New paulomycins produced by Streptomyces paulus.

Autor: Argoudelis AD; Upjohn Company, Kalamazoo, Michigan 49001., Baczynskyj L, Haak WJ, Knoll WM, Mizsak SA, Shilliday FB
Jazyk: angličtina
Zdroj: The Journal of antibiotics [J Antibiot (Tokyo)] 1988 Feb; Vol. 41 (2), pp. 157-69.
DOI: 10.7164/antibiotics.41.157
Abstrakt: Paulomycin A2 (C34H46N2O17S), paulomycin C (C32H42N2O17S), paulomycin D (C31H40N2O17S), paulomycin E (C29H36N2O16S) and paulomycin F (C29H38N2O16S) have been isolated from fermentations of Streptomyces paulus strain 273. The structure of these compounds was determined using NMR and mass spectroscopic techniques. The new paulomycins, like paulomycins A and B (J. Antibiotics 35: 285-294, 1982) are highly active mainly against Gram-positive organisms.
Databáze: MEDLINE