Titanium dental implant-related pathologies: A retrospective histopathological study.

Autor: Paparella ML; Universidad de Buenos Aires, Facultad de Odontología, Cátedra de Anatomía Patológica, Buenos Aires, Argentina., Domingo MG; Universidad de Buenos Aires, Facultad de Odontología, Cátedra de Anatomía Patológica, Buenos Aires, Argentina.; Research Fellow of the University of Buenos Aires, Buenos Aires, Argentina., Puia SA; Universidad de Buenos Aires, Facultad de Odontología, Cátedra de Cirugía I, Buenos Aires, Argentina., Jacobi-Gresser E; Private Practice, Implantology and Environmental Oral Medicine, Mainz, Germany., Olmedo DG; Universidad de Buenos Aires, Facultad de Odontología, Cátedra de Anatomía Patológica, Buenos Aires, Argentina.; National Council of Scientific and Technical Research (CONICET), Buenos Aires, Argentina.
Jazyk: angličtina
Zdroj: Oral diseases [Oral Dis] 2022 Mar; Vol. 28 (2), pp. 503-512. Date of Electronic Publication: 2021 Feb 18.
DOI: 10.1111/odi.13794
Abstrakt: Objectives: To perform a retrospective, descriptive, histopathological study of peri-implant tissue pathologies associated with titanium dental implants (TDI), and to evaluate the presence of metallic particles in samples from a single diagnostic center.
Methods: Sixty-eight cases of TDI-associated lesions were retrieved from the Surgical Pathology Laboratory archives, School of Dentistry, University of Buenos Aires (UBA) (1990-2018). The study included re-examining the histopathological features of the biopsy samples, analyzing the inflammatory infiltrate, and examining the samples to detect metallic particles whose chemical composition was determined spectrophotometrically (EDS). Available clinical and radiographic data were also reviewed.
Results: The retrieved cases ranged from lesions of inflammatory origin to neoplastic lesions. Metallic particles were observed in 36 cases (52.9%), all of which showed inflammation. Particle length ranged from 2 to 85µm. EDS analysis of the particles/deposits observed in the tissues showed the presence of aluminum, titanium, iron, and nickel, among other elements.
Conclusions: A significant number of TDI-associated lesions, including cases not reported to date and diagnosed at a single diagnostic center, are shown here. Cases showing particles exhibited an inflammatory response, irrespective of the histopathological diagnosis. The role of metallic particles in the development of TDI-associated lesion is yet to be established.
(© 2021 Wiley Periodicals LLC.)
Databáze: MEDLINE