First report on the nationwide prevalence of paediatric type 1 diabetes in Serbia and temporal trends of diabetes ketoacidosis at diagnosis-a multicentre study.

Autor:	Stankovic S; Pediatric Endocrinology, Children Clinic, Medical Faculty, Nis, Serbia., Vukovic R; Department of Endocrinology, Mother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', Belgrade, Serbia., Vorgucin I; Endocrinology, Institute for Children and Youth Health Care of Vojvodina, Medical Faculty, Novi Sad, Serbia., Zdravkovic V; Department of Endocrinology, University Children Hospital, Medical Faculty, Belgrade, Serbia., Folic N; Paediatric Clinic, Clinical Centre Kragujevac, Medical Faculty, University of Kragujevac, Serbia., Zivic S; Department of Endocrinology, Pediatric Clinic, Faculty of Medicine Nis, University of Nis, Nis, Serbia., Ignjatovic A; Department of Medical Statistics, University of Niš, Faculty of Medicine Niš, Nis, Serbia., Rancic N; Epidemiology, University of Nis Faculty of Medicine, Nis, Serbia., Milenkovic T; Department of Endocrinology, Mother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', Belgrade, Serbia., Todorovic S; Department of Endocrinology, Mother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', Belgrade, Serbia., Mitrovic K; Department of Endocrinology, Mother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', Belgrade, Serbia., Jesic M; Department of Endocrinology, University Children Hospital, Medical Faculty, Belgrade, Serbia., Sajic S; Department of Endocrinology, University Children Hospital, Medical Faculty, Belgrade, Serbia., Bojic V; Department of Endocrinology, University Children Hospital, Medical Faculty, Belgrade, Serbia., Katanic D; Endocrinology, Institute for Children and Youth Health Care of Vojvodina, Medical Faculty, Novi Sad, Serbia., Dautovic S; Endocrinology, Institute for Children and Youth Health Care of Vojvodina, Novi Sad, Serbia., Cvetkovic V; Department of Endocrinology, Pediatric Clinic, Nis, Serbia., Saranac L; Department of Endocrinology, Pediatric Clinic, Faculty of Medicine Nis, University of Nis, Nis, Serbia., Markovic S; Paediatric Clinic, Clinical Centre Kragujevac, Medical Faculty, University of Kragujevac, Serbia., Tucakovic T; General Hospital Kraljevo, Kraljevo, Serbia., Lesovic S; General Hospital Uzice, Uzice, Serbia., Ljubojevic M; General Hospital Uzice, Uzice, Serbia., Ilic T; General Hospital Subotica, Subotica, Serbia., Vrebalov M; General Hospital Zrenjanin, Zrenjanin, Serbia., Mikic M; General Hospital Cuprija, Cuprija, Serbia., Jelenkovic B; General Hospital Zajeca, Zajeca, Serbia., Petrovic R; General Hospital Cacak, Cacak, Serbia., Saric S; General Hospital Loznica, Loznica, Serbia., Simić D; General Hospital Sombor, Sombor, Serbia., Cukanovic M; Special Hospital Bukovicka Banja, Bukovicka Banja, Serbia., Stankovic M; University of Nis Faculty of Medicine, Nis, Serbia.
Jazyk:	angličtina
Zdroj:	Journal of pediatric endocrinology & metabolism : JPEM [J Pediatr Endocrinol Metab] 2020 Nov 19; Vol. 34 (2), pp. 225-229. Date of Electronic Publication: 2020 Nov 19 (Print Publication: 2021).
DOI:	10.1515/jpem-2020-0405
Abstrakt:	We aimed to collect data on all paediatric patients who were diagnosed with type 1 diabetes mellitus (T1DM) between the years 2000 and 2019 in Serbia and estimate for the first time its prevalence. Also, the trends of diabetes ketoacidosis (DKA) occurrence at the time of diagnosis are monitored. We collected and retrospectively analysed the data of patients <19 years with newly diagnosed T1DM. T1DM was diagnosed in 3134 patients (53.2% male). Total number of youth <19 years with T1DM was 1735 with prevalence of 135.25/100000 at the end of study period. T1DM was diagnosed most frequently between the ages of 5 and 11 years (42.1%). At the time of diagnosis, 35.7% presented in DKA. The incidence and severity of DKA were more significant at the youngest age (p<0.001). There were significant annual percentage increase (2.2%) in the number of new cases of DKA (p=0.007). Conclusion: This first report of nationwide prevalence of T1DM in youth shows that Serbia is among countries with high prevalence of T1DM in youth. System changes are needed in order to provide better quality of health care to these patients. (© 2020 Walter de Gruyter GmbH, Berlin/Boston.)
Databáze:	MEDLINE
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