Underestimation of invasive breast carcinoma in patients with initial diagnosis of ductal carcinoma in situ: Size matters.

Autor: Bouzón Alejandro A; Unidad de Mama, Servicio de Cirugía General, Complejo Hospitalario Universitario A Coruña, España. Electronic address: dr.alberto@aecirujanos.es., Iglesias López Á; Unidad de Mama, Servicio de Radiología, Complejo Hospitalario Universitario A Coruña, España., Acea Nebril B; Unidad de Mama, Servicio de Cirugía General, Complejo Hospitalario Universitario A Coruña, España., García Jiménez ML; Unidad de Mama, Servicio de Cirugía General, Complejo Hospitalario Universitario A Coruña, España., Díaz Carballada CC; Unidad de Mama, Servicio de Ginecología, Complejo Hospitalario Universitario A Coruña, España., Varela Romero JR; Unidad de Mama, Servicio de Radiología, Complejo Hospitalario Universitario A Coruña, España.
Jazyk: English; Spanish; Castilian
Zdroj: Cirugia espanola [Cir Esp (Engl Ed)] 2021 Feb 01. Date of Electronic Publication: 2021 Feb 01.
DOI: 10.1016/j.ciresp.2020.10.020
Abstrakt: Introduction: The aim of our study was to identify those patients with preoperative diagnosis of ductal carcinoma in situ (DCIS) and high risk of upstaging to invasive breast carcinoma (IBC), in whom sentinel lymph node biopsy (SLNB) should be considered.
Methods: One-hundred and five DCIS patients treated with breast-conserving surgery (BCS) or mastectomy were studied. Preoperative features of the tumors were analyzed to investigate its association with underestimation of IBC on final pathology.
Results: Overall, the underestimation rate of IBC was 16.2%. The underestimation rate was highest in lesions with initial size >2 cm compared with those with size ≤2 cm (26.8% vs. 4.1%, respectively; p < 0.003). Eighty-eight patients (83.8%) underwent concurrent SLNB and only one case had lymph node involvement (1.1%).
Conclusions: SLNB should be considered in DCIS patients receiving BCS with lesions greater than 2 cm since approximately one in four will harbor an IBC.
(Copyright © 2020 AEC. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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