Study of degradation of amitriptyline antidepressant by different electrochemical advanced oxidation processes.

Autor: Melin V; Laboratorio de Química Verde, Departamento de Química Analítica e Inorgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 129, Concepción, Chile., Salgado P; Laboratorio de Procesos Químicos Aplicados, Departamento de Ingeniería Civil, Facultad de Ingeniería, Universidad Católica de La Santísima Concepción, Alonso de Ribera 2850, Concepción, Chile., Thiam A; Programa Institucional de Fomento a La Investigación, Desarrollo e Innovación (PIDi), Universidad Tecnológica Metropolitana, Santiago, Chile., Henríquez A; Departamento de Ingeniería Mecánica, Facultad de Ingeniería, Universidad de Tarapacá, Avda. General Velásquez, 1775, Arica, Chile; Laboratorio de Investigaciones Medioambientales de Zonas Áridas, LIMZA, Universidad de Tarapacá, Avda. General Velásquez, 1775, Arica, Chile., Mansilla HD; Laboratorio de Química Orgánica Ambiental, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 129, Concepción, Chile., Yáñez J; Laboratorio de Trazas Elementales y Especiación, Departamento de Química Analítica e Inorgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 129, Concepción, Chile., Salazar C; Laboratorio de Procesos Químicos Aplicados, Departamento de Ingeniería Civil, Facultad de Ingeniería, Universidad Católica de La Santísima Concepción, Alonso de Ribera 2850, Concepción, Chile. Electronic address: casalazar@ucsc.cl.
Jazyk: angličtina
Zdroj: Chemosphere [Chemosphere] 2021 Jul; Vol. 274, pp. 129683. Date of Electronic Publication: 2021 Jan 19.
DOI: 10.1016/j.chemosphere.2021.129683
Abstrakt: Amitriptyline (AMT) is the most widely used tricyclic antidepressant and is classified as a recalcitrant emergent contaminant because it has been detected in different sources of water. Its accumulation in water and soil represents a risk for different living creatures. To remove amitriptyline from wastewater, the Advanced Oxidation Processes (AOPs) stands up as an interesting option since generate highly oxidized species as hydroxyl radicals (OH) by environmentally friendly mechanism. In this work, the oxidation and mineralization of AMT solution have been comparatively studied by 3 Electrochemical AOPs (EAOPs) where the OH is produced by anodic oxidation of H 2 O (AO-H 2 O 2 ), or by electro-Fenton (EF) or photoelectro-Fenton (PEF). PEF process with a BDD anode showed the best performance for degradation and mineralization of this drug due to the synergistic action of highly reactive physiosorbed BDD (OH), homogeneous OH and UVA radiation. This process achieved total degradation of AMT at 50 min of electrolysis and 95% of mineralization after 360 min of treatment with 0.5 mmol L -1 Fe 2+ at 100 mA cm -2 . Six aromatic intermediates for the drug mineralization were identified in short time of electrolysis by GC-MS, including a chloroaromatic by-product formed from the attack of active chlorine. Short-chain carboxylic acids like succinic, malic, oxalic and formic acid were quantified by ion-exclusion HPLC. Furthermore, the formation of NO 3 - ions was monitored. Finally, the organic intermediates identified by chromatographic techniques were used to propose the reaction sequence for the total mineralization of AMT.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2021 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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